Α-鹅膏蕈碱

中文名称： Α-鹅膏蕈碱

英文名称： α-Amanitin

CAS： 11030-71-0

分子式： C₃₉H₅₃N₉O₁₄S

分子量： 904

EINECS号：

中文同义词 Α-鹅膏蕈碱英文同义词

α-Amanitin

基本性质

熔点	245 °C (decomp)

安全信息

毒性	A drug derived from the highly poisonous fungus Amanita phalloides (death cap). Alpha-amanitin, a cyclic octapeptide, is toxic because of its affinity for RNA polymerase II in eukaryotic cells. Since this enzyme is responsible for mRNA synthesis in the cell, the compound is a potent and selective inhibitor of mRNA synthesis. It is effective at concentrations below 1 μg/mL, and its specific action has made it useful in experimental biology. It is often used with actinomycin D to block RNA synthesis.

毒性

A drug derived from the highly poisonous fungus Amanita phalloides (death cap). Alpha-amanitin, a cyclic octapeptide, is toxic because of its affinity for RNA polymerase II in eukaryotic cells. Since this enzyme is responsible for mRNA synthesis in the cell, the compound is a potent and selective inhibitor of mRNA synthesis. It is effective at concentrations below 1 μg/mL, and its specific action has made it useful in experimental biology. It is often used with actinomycin D to block RNA synthesis.

CHS信息

生产方法及用途

供应商

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上海熹垣生物科技有限公司

产品名称： α-Amanitin

CAS： 11030-71-0

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