(E)-位变异烟碱

中文名称： (E)-位变异烟碱

英文名称： rivanicline

CAS： 15585-43-0

分子式： C₁₀H₁₄N₂

分子量： 162

EINECS号：

中文同义词 (E)-位变异烟碱英文同义词

rivanicline

基本性质

沸点	99-101°C/0.4mm Hg
密度	0.980
闪点	130℃
溶解度	Soluble in DMSO
形态	Powder
酸度系数(pKa)	10.03±0.10(Predicted)

安全信息

CHS信息

生产方法及用途

用途	An alkaloid found in the leaves of Duboisia Hopwoodii, and a constitutent of tobacco smoke. Also used a potential drug for the treatment of senile dementia of the Alzheimer鈥檚 type and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to periphera l ganglionic and muscle-type nicotinic acetylcholine receptors.

用途

An alkaloid found in the leaves of Duboisia Hopwoodii, and a constitutent of tobacco smoke. Also used a potential drug for the treatment of senile dementia of the Alzheimer鈥檚 type and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to periphera l ganglionic and muscle-type nicotinic acetylcholine receptors.