6-氨基-8-[(6-碘-1,3-苯并二茂-5-基)硫基]-N-异丙基-9H-嘌呤-9-丙胺

中文名称： 6-氨基-8-[(6-碘-1,3-苯并二茂-5-基)硫基]-N-异丙基-9H-嘌呤-9-丙胺

英文名称： 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine

CAS： 873436-91-0

分子式： C₁₈H₂₁IN₆O₂S

分子量： 512

EINECS号：

中文同义词 6-氨基-8-[(6-碘-1,3-苯并二茂-5-基)硫基]-N-异丙基-9H-嘌呤-9-丙胺英文同义词

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine

基本性质

熔点	>194oC (dec.)
溶解度	DMSO (Slightly), Methanol (Slightly)
形态	Solid
酸度系数(pKa)	10.16±0.29(Predicted)
颜色	Off-White to Pale Beige

用途	PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Stu dies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson鈥瞫 disease.