甲基巴多索隆

中文名称：甲基巴多索隆

英文名称： Bardoxolone methyl

CAS： 218600-53-4

分子式： C₃₂H₄₃NO₄

分子量： 506

EINECS号： 606-850-4

中文同义词甲基巴多索隆英文同义词

Bardoxolone methyl

基本性质

熔点	215-223°C
溶解度	Chloroform (Slightly), Methanol (Slightly)
形态	Solid
颜色	White to Light Brown

安全信息

CHS信息

危险性符号(GHS)	GHS08
警示词	Warning

生产方法及用途

用途	CDDO Methyl Ester is a synthetic triterpenoid that inhibits I κBα kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor κB-reg ulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer.

用途

CDDO Methyl Ester is a synthetic triterpenoid that inhibits I κBα kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor κB-reg ulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer.