产品名称

英文名称：Nivalenol from Fusarium nivale

同义词

Trichothec-9-en-8-one,12,13-epoxy-3a,4b,7a,15-tetrahydroxy-(8CI)、12,13-Epoxy-3a,4b,7a,15-tetrahydroxytrichothec-9-en-8-one、3a,4b,7a,15-Tetrahydroxyscrip-9-en-8-one、NSC 269143、Nivalenol、NSC 269143、12,13-EPOXY-3.ALPHA.,4.BETA.,7.ALPHA.,15-TETRAHYDROXYTRICHO、3α,4β,7α,15-Tetrahydroxy-12,13-epoxytrichothec-9-en-8-one

产品性质

CAS编号：23282-20-4

分子式：C15H20O7

分子量：312.3

MDL号：MFCD00133673

PubChem编号：5284433

别名：3α,4β,7α,15-Tetrahydroxy-12,13-epoxytrichothec-9-en-8-one

英文别名：Trichothec-9-en-8-one,12,13-epoxy-3a,4b,7a,15-tetrahydroxy-(8CI)|12,13-Epoxy-3a,4b,7a,15-tetrahydroxytrichothec-9-en-8-one|3a,4b,7a,15-Tetrahydroxyscrip-9-en-8-one|NSC 269143|Nivalenol|NSC 269143|12,13-EPOXY-3.ALPHA.,4.BETA.,7.ALPHA.,15-TETRAHYDROXYTRICHO

规格或纯度：≥99.0%(HPLC)

英文名称：Nivalenol from Fusarium nivale

生化机理：天花粉菌毒素。体外细胞毒性（EC 50 = 0.96μM）。减少细胞增殖。促凋亡活性。在体外和体内具有活性。

来源：Fusarium sp.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Nivalenol is a type - B trichothecene mycotoxin, produced by molds such as Fusarium cerealis, Fusarium graminearum. Nivalenol may be formed by higher plants and by mamals, as a productt of biodegradation of other thrichothecenes.Nivalenol (0.01 mg/ml) induces apoptosis in HL60 cells (Ueno et al., 1995). Nivalenol was shown to inhibit protein synthesis in rabbit reticulocytes in vitro. Nivalenol inhibited the synthesis of nucleic acids in vitro (Ueno and Fukushima, 1968)Nivalenol is a type - B trichothecene mycotoxin, produced by molds such as Fusarium cerealis, Fusarium graminearum. Nivalenol may be formed by higher plants and by mamals, as a productt of biodegradation of other thrichothecenes.Nivalenol (0.01 mg/ml) induces apoptosis in HL60 cells (Ueno et al., 1995). Nivalenol was shown to inhibit protein synthesis in rabbit reticulocytes in vitro. Nivalenol inhibited the synthesis of nucleic acids in vitro (Ueno and Fukushima, 1968)

IUPAC Name：(1S,2R,3S,7R,9R,10R,11S,12S)-3,10,11-trihydroxy-2-(hydroxymethyl)-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one

INCHI：InChI=1S/C15H20O7/c1-6-3-7-14(4-16,11(20)8(6)17)13(2)10(19)9(18)12(22-7)15(13)5-21-15/h3,7,9-12,16,18-20H,4-5H2,1-2H3/t7-,9-,10-,11-,12-,13-,14-,15+/m1/s1

InChi Key：UKOTXHQERFPCBU-XBXCNEFVSA-N

Canonical SMILES：CC1=CC2C(C(C1=O)O)(C3(C(C(C(C34CO4)O2)O)O)C)CO

Isomeric SMILES：CC1=C[C@@H]2[C@]([C@@H](C1=O)O)([C@]3([C@@H]([C@H]([C@H]([C@@]34CO4)O2)O)O)C)CO

WGK Germany：3

PubChem CID：5284433

溶解性：Dichloromethane, DMSO, Methanol. Slightly soluble in water,

敏感性：对光线敏感

熔点：127°C-130°C

象形图：

信号词：Danger

危险声明：H300 Fatal if swallowedH310 Fatal in contact with skinH330 Fatal if inhaled

预防措施声明：P280,P302+P352,P321,P405,P501,P264,P260,P284,P271,P270,P304+P340,P403+P233,P330,P262,P320,P361+P364,P301+P316,P316

个人防护装备：Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

产品包装