产品名称

英文名称：Gatifloxacin

同义词

HMS3259P06、AM-1155、Spectrum3_000999、PD-135432、CHEBI5280、RKL10068、1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid、AKOS016340697、AM 1155、CS-1841、NC00702、SCHEMBL22591、Spectrum5_001468、HMS2093G06、Tequin、BMS 206584、加替沙星

产品性质

CAS编号：112811-59-3

分子式：C19H22FN3O4

分子量：375.39

PubChem编号：5379

别名：加替沙星

英文别名：HMS3259P06|AM-1155|Spectrum3_000999|PD-135432|CHEBI5280|RKL10068|1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid|AKOS016340697|AM 1155|CS-1841|NC00702|SCHEMBL22591|Spectrum5_001468|HMS2093G06|Tequin|BMS 206584

规格或纯度：≥98%

英文名称：Gatifloxacin

生化机理：Gatifloxacin is a fluoroquinolone antibiotic, with potent activity against Gram-negative and Gram-positive bacteria. Gatifloxacin also inhibits bacterial topoismerase II (Topo II).Fluoroquinolone antibiotic. Inhibits bacterial DNA gyrase and type II topoisomerase (IC 50 values are 0.109 and 13.8 µg/ml respectively. Pharmacologically active following oral administration. Crosses the blood-brain barrier.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：atifloxacin是第四代喹诺酮类抗生素。A fluoroquinolone antibiotic and inhibitor of type II bacterial topoisomerases.Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, and inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.A fluoroquinolone antibiotic and inhibitor of type II bacterial topoisomerases.

ALogP：-0.7

IUPAC Name：1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid

INCHI：InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)

InChi Key：XUBOMFCQGDBHNK-UHFFFAOYSA-N

Canonical SMILES：CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F

Isomeric SMILES：CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F

PubChem CID：5379

CAS Registry No.：112811-59-3

Antibiotic DB：940

DrugCentral Ligand：1280

溶解性：Soluble in water at pH 2-5 (40-60 mg/ml), chloroform, methanol (Sparingly), DMSO (10 mM), and ethanol (<1 mg/mL).

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowedH312 Harmful in contact with skinH332 Harmful if inhaled

预防措施声明：P261,P280,P302+P352,P321,P501,P264,P271,P270,P304+P340,P362+P364,P330,P301+P317,P317

产品包装