产品名称

英文名称：Protoporphyrin IX

同义词

protoporphyrin IX、protoporphyrin、553-12-8、Ooporphyrin、Protoporpyrin IX、Porphyrinogen IX、Protoporphyrin IX disodium、Kammerer's prophyrin、ppIX、H2ppIX、Kammerer's porphyrin、MLS001074731、3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihy、Kammerer's porphyrin 蛋壳卟啉、3,7,12,17-四甲基-8,13-二乙烯基-2,18-卟吩二丙酸

产品性质

CAS编号：553-12-8

分子式：C34H34N4O4

分子量：562.66

Beilstein号：380795

EC号：209-033-7

MDL号：MFCD00151109

PubChem编号：4971

别名：Kammerer's porphyrin 蛋壳卟啉|3,7,12,17-四甲基-8,13-二乙烯基-2,18-卟吩二丙酸

英文别名：protoporphyrin IX|protoporphyrin|553-12-8|Ooporphyrin|Protoporpyrin IX|Porphyrinogen IX|Protoporphyrin IX disodium|Kammerer's prophyrin|ppIX|H2ppIX|Kammerer's porphyrin|MLS001074731|3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihy

规格或纯度：≥95%

英文名称：Protoporphyrin IX

生化机理：原卟啉IX可以穿透人体红细胞并帮助它们释放氧气。它可与肌红蛋白和血红蛋白形成复合物。它可用作癌症光动力疗法的光敏剂。

储存温度：2-8°C储存,避光

运输条件：冰袋运输

产品介绍：原卟啉IX使血红素呈红色，是血液中的主要卟啉。在存在原卟啉原IX氧化酶的条件下，其由原卟啉原IX合成。原卟啉IX属于卟啉家族，是一类四吡咯。它是氯高铁血红素的无铁形式，并且天然具有两亲性质。它是生物合成途径中血红素的前体。应用原卟啉IX已被用于作为原卟啉测定的标准品；荧光光谱分析中；处理细胞培养中的细胞以研究血红素介导的铁转运蛋白1的转录；可激活可溶性鸟苷酸环化酶。 General descriptionProtoporphyrin IX belongs to the porphyrin family, which are aclass of tetrapyrroles. It is the iron-free form of hemin and amphiphilic in nature. It is the precursor of heme in its biosynthetic pathway.Protoporphyrin IX imparts red color to heme and is the major porphyrin in blood. It is synthesized from protoporphyrinogen IX in the presence of protoporphyrinogen IX oxidase.ApplicationProtoporphyrin IX has been usedas astandard in protoporphyrin assays；in fluorescence spectra analysis；to treat cells in cell culture to study heme-mediated ferroportin 1transcription；Activates soluble guanylyl cyclase.

IUPAC Name：3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid

INCHI：InChI=1S/C34H34N4O4/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25/h7-8,13-16,35-36H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42)

InChi Key：ZCFFYALKHPIRKJ-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C=C)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C=C

Isomeric SMILES：CC1=C(C2=CC3=NC(=CC4=NC(=CC5=C(C(=C(N5)C=C1N2)C=C)C)C(=C4CCC(=O)O)C)C(=C3C)CCC(=O)O)C=C

WGK Germany：3

PubChem CID：4971

溶解性：Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), chloroform, glacial acetic acid, alcohol containing hydrochloric acid, ether containing glacial acetic acid, hydrochloric acid, dilute alkalies, aniline, and pyridine. Insoluble in disodium salts, and dipota

敏感性：对光敏感

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：dust mask type N95 (US),Eyeshields,Gloves

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