产品名称

英文名称：6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine

同义词

ENMD-2076、934353-76-1、ENMD 2076、(E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine、ENMD2076、CHEMBL482968、J6U9WP10T7、ENMD-981693、934353-76-1 (free base)、Enmd-2076 free base、6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazo

产品性质

CAS编号：934353-76-1

分子式：C21H25N7

分子量：375.47

PubChem编号：16041424

英文别名：ENMD-2076|934353-76-1|ENMD 2076|(E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine|ENMD2076|CHEMBL482968|J6U9WP10T7|ENMD-981693|934353-76-1 (free base)|Enmd-2076 free base|6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazo

规格或纯度：≥99%

英文名称：6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine

生化机理：ENMD-2076 is a antiangiogenic and Aurora kinase inhibitor with IC50 of 3, 13, 350, 23, 40, 93 and 120 nM for Flt-3, AurA, AurB, Src, KDR/VEGFR2 and FGFR1.

储存温度：-20°C储存

运输条件：超低温冰袋运输

ALogP：3.7

IUPAC Name：6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine

INCHI：InChI=1S/C21H25N7/c1-16-14-20(26-25-16)23-19-15-21(28-12-10-27(2)11-13-28)24-18(22-19)9-8-17-6-4-3-5-7-17/h3-9,14-15H,10-13H2,1-2H3,(H2,22,23,24,25,26)/b9-8+

InChi Key：BLQYVHBZHAISJM-CMDGGOBGSA-N

Canonical SMILES：CC1=CC(=NN1)NC2=CC(=NC(=N2)C=CC3=CC=CC=C3)N4CCN(CC4)C

Isomeric SMILES：CC1=CC(=NN1)NC2=CC(=NC(=N2)/C=C/C3=CC=CC=C3)N4CCN(CC4)C

PubChem CID：16041424

CAS Registry No.：934353-76-1

ChEMBL Ligand：CHEMBL482968

RCSB PDB Ligand：J3A

溶解性：DMSO 105 mg/mL Water 1 mg/mL Ethanol <1 mg/mL

产品包装