产品名称

英文名称：Amitriptyline Hydrochloride

同义词

Amitriptyline hydrochloride、549-18-8、Amitriptyline HCl、Annoyltin、Tryptizol、Domical、Syneudon、Etravil、Endep、Elavil hydrochloride、Lentizol、Novoprotect、Amavil、Amitid、Amitril、Saroten、Ami-Anelun、Mitaptyline、Yamanouchi、Amineurin、Amiplin、Amiprin、Amitrip、Amyline、A、盐酸阿米替林

产品性质

CAS编号：549-18-8

分子式：C20H23N · HCl

分子量：313.86

EC号：208-964-6

MDL号：MFCD00012537

PubChem编号：11065

别名：盐酸阿米替林

英文别名：Amitriptyline hydrochloride|549-18-8|Amitriptyline HCl|Annoyltin|Tryptizol|Domical|Syneudon|Etravil|Endep|Elavil hydrochloride|Lentizol|Novoprotect|Amavil|Amitid|Amitril|Saroten|Ami-Anelun|Mitaptyline|Yamanouchi|Amineurin|Amiplin|Amiprin|Amitrip|Amyline|A

规格或纯度：≥98%

英文名称：Amitriptyline Hydrochloride

生化机理：三环抗抑郁剂；抑制分别具有 100nM 和 14.7nM Kis 的去甲肾上腺素和 5-羟色胺转运蛋白；对 α1-肾上腺素受体、5-羟色胺和毒蕈碱型乙酰胆碱受体具有高度的体外亲和力。血清素和去甲肾上腺素摄取抑制剂。三环抗抑郁药（TCA）。显示抗抑郁和镇痛活性。体内具有活性

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.Amitriptyline hydrochloride is a tricyclic antidepressant drμg. Amitriptyline hydrochloride inhibits the norepinephrine and serotonin transporters but has a high affinity for α1-adrenergic, serotonin and muscarinic acetylcholine receptors.Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.Amitriptyline hydrochloride is a tricyclic antidepressant drug. Amitriptyline hydrochloride inhibits the norepinephrine and serotonin transporters but has a high affinity for α1-adrenergic, serotonin and muscarinic acetylcholine receptors.

PubChem SID：488181249

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488181249

IUPAC Name：N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine;hydrochloride

INCHI：InChI=1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H

InChi Key：KFYRPLNVJVHZGT-UHFFFAOYSA-N

Canonical SMILES：CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

Isomeric SMILES：CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl

WGK Germany：3

RTECS：HO9450000

关联CAS：50-48-6

PubChem CID：11065

溶解性：Soluble in Chloroform

敏感性：对光敏感

熔点：195 °C

象形图：

信号词：Danger

危险声明：H319 Causes serious eye irritationH301 Toxic if swallowedH302 Harmful if swallowedH318 Causes serious eye damageH400 Very toxic to aquatic lifeH410 Very toxic to aquatic life with long lasting effectsH370 Causes damage to organsH361 Suspected of damaging fertility or the unborn childH362 May cause harm to breast-fed children

预防措施声明：P305+P351+P338,P273,P280,P321,P405,P501,P264,P260,P270,P391,P330,P263,P203,P264+P265,P301+P316,P301+P317,P305+P354+P338,P318,P317,P337+P317,P308+P316

Merck Index：487

个人防护装备：Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

产品包装