产品名称

英文名称：Uridine 5’-Diphospho-N-acetylglucosamine Disodium Salt

同义词

91183-98-1、Uridine 5'-diphospho-N-acetylglucosamine sodium salt、UDP-GlcNAc Disodium Salt、Uridine 5'-diphospho-N-acetylglucosamine disodium salt、UDP-N-acetyl-D-glucosamine disodium salt、UDP-、A-D-N-Acetylglucosamine Disodium Salt、disodium;[(2R,3R,4R,5S,6R)-、尿苷 5'-(三氢二磷酸酯) P'-[2-(乙酰氨基)-2-脱氧-alpha-D-吡喃葡萄糖基]酯钠盐(12)、5'-二磷酸尿嘧啶核苷-N-乙酰半乳糖胺二钠盐、UDP-GlcNAc、UDPAG、UDP-N-乙酰葡糖胺

产品性质

CAS编号：91183-98-1

分子式：C17H25N3O17P2Na2

分子量：651.32

EC号：293-820-5

MDL号：MFCD00799985

PubChem编号：16069658

别名：尿苷 5'-(三氢二磷酸酯) P'-[2-(乙酰氨基)-2-脱氧-alpha-D-吡喃葡萄糖基]酯钠盐(12)|5'-二磷酸尿嘧啶核苷-N-乙酰半乳糖胺二钠盐|UDP-GlcNAc|UDPAG|UDP-N-乙酰葡糖胺|

英文别名：91183-98-1|Uridine 5'-diphospho-N-acetylglucosamine sodium salt|UDP-GlcNAc Disodium Salt|Uridine 5'-diphospho-N-acetylglucosamine disodium salt|UDP-N-acetyl-D-glucosamine disodium salt|UDP-|A-D-N-Acetylglucosamine Disodium Salt|disodium;[(2R,3R,4R,5S,6R)-

规格或纯度：≥98%

英文名称：Uridine 5’-Diphospho-N-acetylglucosamine Disodium Salt

生化机理：供体底物可用于在合成N-聚糖中将GlcNAc转移至多萜醇前体。 UDP-GlcNAc还在O-GlcNAc信号转导中通过O-GlcNAc转移酶（OGT）作为与丝氨酸/苏氨酸残基连接的GlcNAc的来源。N聚糖合成中将GlcNAc转移至二元醇前体的供体底物。在O-GlcNAc信号转导中，还用作通过O-GlcNAc转移酶（OGT）连接到丝氨酸/苏氨酸残基的GlcNAc的来源。

应用：Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) sodium salt has been used · as a component of reaction cocktail in endoplasmic reticulum to Golgi transport assay · as a reference standard for the quantification of UDP-GlcNAc in liver tissues using high-performance liquid chromatography (HPLC) · in testing the glycosylation activity of O-GlcNAc transferase (OGT) against peptide substrate

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a nucleotide sμgar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP). UDP-GlcNAc is transported actively into Golgi, nucleotide sμgar transporter (NST). The levels of UDP-GlcNAc is modulated by the concentration of nutrients exposed to the cell.Uridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) sodium salt has been used · as a component of reaction cocktail in endoplasmic reticulum to Golgi transport assay · as a reference standard for the quantification of UDP-GlcNAc in liver tissues using high-performance liquid chromatography (HPLC) · in testing the glycosylation activity of O-GlcNAc transferase (OGT) against peptide substrateUridine 5′-diphospho-N-acetylglucosamine (UDP-GlcNAc) is a nucleotide sugar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP). UDP-GlcNAc is transported actively into Golgi, nucleotide sugar transporter (NST). The levels of UDP-GlcNAc is modulated by the concentration of nutrients exposed to the cell.

IUPAC Name：disodium;[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate

INCHI：InChI=1S/C17H27N3O17P2.2Na/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28;;/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28);;/q;2*+1/p-2/t7-,8-,10-,11-,12-,13-,14-,15-,16-;;/m1../s1

InChi Key：HXWKMJZFIJNGES-YZVFIFBQSA-L

Canonical SMILES：CC(=O)NC1C(C(C(OC1OP(=O)([O-])OP(=O)([O-])OCC2C(C(C(O2)N3C=CC(=O)NC3=O)O)O)CO)O)O.[Na+].[Na+]

Isomeric SMILES：CC(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1OP(=O)([O-])OP(=O)([O-])OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC(=O)NC3=O)O)O)CO)O)O.[Na+].[Na+]

WGK Germany：3

PubChem CID：16069658

溶解性：DMSO 10mM( < 1 mg/ml refers to the product slightly soluble or insoluble )

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

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