达非那新

产品分类

应用/药物靶标/G蛋白偶联受体（GPCR）/乙酰胆碱受体（毒蕈碱）

产品名称

中文名称：达非那新

英文名称：Darifenacin

同义词

Darifenacin、133099-04-4、Enablex、UK-88525、UNII-APG9819VLM、Darifenacin extended release、APG9819VLM、2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide、CHEBI391960、(S)-1-(2-(2,3-Dihydro-5-benzofuranyl)ethyl)-alpha,alpha-

产品性质

CAS编号：133099-04-4

分子式：C28H30N2O2

分子量：426.55

EC号：603-704-1

PubChem编号：444031

英文名称：Darifenacin

生化机理：Darifenacin is a selectivity M3 receptor antagonist and newer antimuscarinic agents. Darifenacin is indicated for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency and frequency in adults.

储存温度：-20°C储存

运输条件：超低温冰袋运输

IUPAC Name：2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide

INCHI：InChI=1S/C28H30N2O2/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26/h1-12,19,25H,13-18,20H2,(H2,29,31)/t25-/m1/s1

InChi Key：HXGBXQDTNZMWGS-RUZDIDTESA-N

Canonical SMILES：C1CN(CC1C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)N)CCC4=CC5=C(C=C4)OCC5

关联CAS：133099-04-4

PubChem CID：444031

MeSH Entry Terms：(S)-1-(2-(2,3-dihydro-5-benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide;darifenacin;darifenacin hydrobromide;darifenacin hydrochloride;darifenacine;darifenicin;Emselex;Enablex;UK-88525

ChEMBL Ligand：CHEMBL1346

DrugBank Ligand：DB00496

Wikipedia：Darifenacin

CAS Registry No.：133099-04-4

ChEBI：CHEBI391960

PEP：darifenacin

DrugCentral Ligand：784

GPCRdb Ligand：darifenacin

溶解性：DMSO

产品包装