产品名称

英文名称：Sodium dodecyl sulfate

同义词

Sodium dodecyl sulfate、151-21-3、SODIUM LAURYL SULFATE、Sodium dodecylsulfate、Sodium lauryl sulphate、Sodium dodecyl sulphate、Neutrazyme、Sodium n-dodecyl sulfate、Irium、Sulfuric acid monododecyl ester sodium salt、Dodecyl sulfate sodium salt、Dodecyl sodium sul、SDS,月桂基硫酸钠,月桂基硫酸盐钠盐

产品性质

CAS编号：151-21-3

分子式：CH3(CH2)11OSO3Na

分子量：288.38

EC号：205-788-1

MDL号：MFCD00036175

PubChem编号：3423265

别名：SDS,月桂基硫酸钠,月桂基硫酸盐钠盐

英文别名：Sodium dodecyl sulfate|151-21-3|SODIUM LAURYL SULFATE|Sodium dodecylsulfate|Sodium lauryl sulphate|Sodium dodecyl sulphate|Neutrazyme|Sodium n-dodecyl sulfate|Irium|Sulfuric acid monododecyl ester sodium salt|Dodecyl sulfate sodium salt|Dodecyl sodium sul

规格或纯度：AR,92.5-100.5%

英文名称：Sodium dodecyl sulfate

生化机理：十二烷基硫酸钠（SDS）是一种阴离子去污剂，可通过疏水相互作用与蛋白质形成复合物。已有研究报道称蛋白质-SDS复合物的流体动力学功能受其多肽链长度的控制。因此，基于SDS的电泳技术可根据蛋白质的分子量而将蛋白质分子进行分离。此外，SDS还可溶解细胞膜并提取膜结合蛋白。

运输条件：常规运输

产品介绍：有特殊气味。溶于水呈不透明溶液，溶液呈中性。能乳化脂肪。有湿热空气中分解。有光滑感。1g溶于10ml水中，形成乳状液，水溶液表面张力小，呈中性反应，部分溶于乙醇，几乎不溶于氯仿、乙醚和轻石油。低毒，半数致死量(大鼠，经口)1288mg/kg。有刺激性。溶解度150 g/l 水 (20°C)，75 g/l 乙醇 (20°C)应用十二烷基硫酸钠被用作一种检测化合物，用于研究解淀粉芽孢杆菌KPS46是否能在大豆（Glycine maxL.）中诱导针对几种疾病的引发、信号传导、蛋白质产生以及系统保护。十二烷基硫酸钠（SDS）是一种阴离子去污剂，可通过疏水相互作用与蛋白质形成复合物。已有研究报道称蛋白质-SDS复合物的流体动力学功能受其多肽链长度的控制。因此，基于SDS的电泳技术可根据蛋白质的分子量而将蛋白质分子进行分离。此外，SDS还可溶解细胞膜并提取膜结合蛋白。 Sodium dodecyl sulfate (SDS), also known as sodium lauryl sulfate, is a versatile anionic surfactant with a broad range of applications in cell biology, biochemistry, and various industries. Its amphiphilic nature, characterized by a hydrophobic hydrocarbon tail and a hydrophilic sulfate head group, makes it an effective detergent capable of solubilizing and denaturing proteins, lipids, and other hydrophobic molecules.In protein biochemistry, SDS plays a pivotal role in protein extraction and SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis). Its ability to denature proteins by disrupting their secondary and tertiary structures allows for their uniform migration through a polyacrylamide gel matrix based on their molecular weight. This technique, SDS-PAGE, has become an indispensable tool for analyzing protein size and purity.Beyond protein analysis, SDS also finds applications in nucleic acid extraction and hybridization techniques. Its detergent properties aid in the lysis of cells and the solubilization of cellular components, facilitating the extraction of DNA and RNA. This makes SDS a valuable reagent in various molecular biology protocols, including PCR (polymerase chain reaction) and Southern blotting. Sodium dodecyl sulfate stands as a versatile and widely used surfactant with a diverse range of applications due to its ability to solubilize, denature, and separate biological molecules for cell biology and biochemical research.

IUPAC Name：sodium;dodecyl sulfate

INCHI：InChI=1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChi Key：DBMJMQXJHONAFJ-UHFFFAOYSA-M

Canonical SMILES：[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

Isomeric SMILES：CCCCCCCCCCCCOS(=O)(=O)[O-].[Na+]

PubChem CID：3423265

溶解性：Soluble in water

密度：1.01

敏感性：易吸湿,对空气敏感

熔点：204-207°C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH373 Causes damage to organs through prolonged or repeated exposureH401 Toxic to aquatic life

预防措施声明：P261,P305+P351+P338,P273,P280,P370+P378,P310,P302+P352,P405,P501,P312,P264,P271,P270,P304+P340,P337+P313,P403+P233,P332+P313,P391,P330,P301+P312

Class：4.1

Merck Index：8636

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