产品名称

英文名称：Anamorelin

同义词

RC-1291、CCG-269985、UNII-6MUC9717YK、HY-14734、RC-1291;ONO-7643、ST-1291、UNII-DD5RBA1NKF、Q20707542、RC-1291、AKOS030526752、BCP06108、2-Methyl-4-(2-phenyldiazenyl)phenol、Anamorelin、ANAMORELIN [WHO-DD]、DB06645、CCG-5137、RC 1291、DD5RBA1NKF、ONO-7643;Anamorelin、SCHEMB、阿拉莫林

产品性质

CAS编号：249921-19-5

分子式：C31H42N6O3

分子量：546.7

PubChem编号：9828911

别名：阿拉莫林

英文别名：RC-1291|CCG-269985|UNII-6MUC9717YK|HY-14734|RC-1291;ONO-7643|ST-1291|UNII-DD5RBA1NKF|Q20707542|RC-1291|AKOS030526752|BCP06108|2-Methyl-4-(2-phenyldiazenyl)phenol|Anamorelin|ANAMORELIN [WHO-DD]|DB06645|CCG-5137|RC 1291|DD5RBA1NKF|ONO-7643;Anamorelin|SCHEMB

规格或纯度：≥98%

英文名称：Anamorelin

生化机理：Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia.Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia.

IUPAC Name：2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide

INCHI：InChI=1S/C31H42N6O3/c1-30(2,32)28(39)34-26(18-23-20-33-25-15-10-9-14-24(23)25)27(38)37-17-11-16-31(21-37,29(40)36(5)35(3)4)19-22-12-7-6-8-13-22/h6-10,12-15,20,26,33H,11,16-19,21,32H2,1-5H3,(H,34,39)/t26-,31-/m1/s1

InChi Key：VQPFSIRUEPQQPP-MXBOTTGLSA-N

Canonical SMILES：CC(C)(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)N3CCCC(C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N

Isomeric SMILES：CC(C)(C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N3CCC[C@](C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N

PubChem CID：9828911

溶解性：DMSO

产品包装