产品名称

英文名称：Radezolid

同义词

Radezolid、869884-78-6、RX-1741、RX-103、N-[[(5S)-3-[2-Fluoro-4'-[[(1H-1,2,3-triazol-5-ylmethyl)amino]methyl][1,1'-biphenyl]-4-yl]-2-oxo-5-oxazolidinyl]methyl]acetamide、rx103、RX-01_667、53PC6LO35W、MMV688327、RX-013、RX1741、(S)-N-((3-(4'-((((1H-1,2,3-triazol-5-yl

产品性质

CAS编号：869884-78-6

分子式：C22H23FN6O3

分子量：438.45

PubChem编号：11224409

英文别名：Radezolid|869884-78-6|RX-1741|RX-103|N-[[(5S)-3-[2-Fluoro-4'-[[(1H-1,2,3-triazol-5-ylmethyl)amino]methyl][1,1'-biphenyl]-4-yl]-2-oxo-5-oxazolidinyl]methyl]acetamide|rx103|RX-01_667|53PC6LO35W|MMV688327|RX-013|RX1741|(S)-N-((3-(4'-((((1H-1,2,3-triazol-5-yl

规格或纯度：≥96%

英文名称：Radezolid

生化机理：Radezolid (INN, codenamed RX-1741) is a novel oxazolidinone antibiotic being developed by Rib-X Pharmaceuticals, Inc. for the treatment of serious multi-drμg–resistant infections. Radezolid has completed two phase-II clinical trials. One of these clinical trials was for uncomplicated skin and skin-structure infections (uSSSI) and the other clinical trial was for community acquired pneumonia (CAP). From Wikipedia

储存温度：-20°C储存

运输条件：超低温冰袋运输

ALogP：1.1

IUPAC Name：N-[[(5S)-3-[3-fluoro-4-[4-[(2H-triazol-4-ylmethylamino)methyl]phenyl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

INCHI：InChI=1S/C22H23FN6O3/c1-14(30)25-12-19-13-29(22(31)32-19)18-6-7-20(21(23)8-18)16-4-2-15(3-5-16)9-24-10-17-11-26-28-27-17/h2-8,11,19,24H,9-10,12-13H2,1H3,(H,25,30)(H,26,27,28)/t19-/m0/s1

InChi Key：BTTNOGHPGJANSW-IBGZPJMESA-N

Canonical SMILES：CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)C3=CC=C(C=C3)CNCC4=NNN=C4)F

Isomeric SMILES：CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)C3=CC=C(C=C3)CNCC4=NNN=C4)F

PubChem CID：11224409

CAS Registry No.：869884-78-6

ChEMBL Ligand：CHEMBL455461

DrugBank Ligand：DB12339

RCSB PDB Ligand：RD8

Antibiotic DB：166, 820

溶解性：DMSO

产品包装