产品名称

英文名称：Meloxicam

同义词

meloxicam、71125-38-7、Mobic、Metacam、Movalis、Movatec、Mobec、Mobicox、Coxicam、Meloxivet、Melfax、Meloxicam (Mobic)、UH-AC 62XX、Meloxicamum、Meloxidolor、Meloxoral、Rheumocam、Vivlodex、Melosus、Parocin、Meloxicamum [Latin]、4-Hydroxy-2-methyl-N-(5-methylthiazol-2-yl)-2H-、美洛昔康、UH-AC 62XX、4-羟基-2-甲基-N-(5-甲基-2-噻唑基)-2H-1,2-苯并噻嗪-3-甲酰胺1,1-二氧化物

产品性质

CAS编号：71125-38-7

分子式：C14H13N3O4S2

分子量：351.4

MDL号：MFCD00868752

PubChem编号：54677470

别名：美洛昔康|UH-AC 62XX|4-羟基-2-甲基-N-(5-甲基-2-噻唑基)-2H-1,2-苯并噻嗪-3-甲酰胺1,1-二氧化物

英文别名：meloxicam|71125-38-7|Mobic|Metacam|Movalis|Movatec|Mobec|Mobicox|Coxicam|Meloxivet|Melfax|Meloxicam (Mobic)|UH-AC 62XX|Meloxicamum|Meloxidolor|Meloxoral|Rheumocam|Vivlodex|Melosus|Parocin|Meloxicamum [Latin]|4-Hydroxy-2-methyl-N-(5-methylthiazol-2-yl)-2H-

规格或纯度：≥98%

英文名称：Meloxicam

生化机理：Meloxicam, a non-steroidal anti-inflammatory agent, has been reported to inhibit the inducible isoform of Cox-2. Meloxicam is an inhibitor selective for Cox-2 (IC50 of 4.7 μM) over Cox-1 (IC50 of 36.6 μM). Studies sμggest that Meloxicam is Cox-2 preferential, therefore it will probably not display a lower gastrointestinal toxicity than non-selective anti-inflammatory agents. This compound has been shown to also inhibit prostanoid synthesis in inflammatory cells. Additionally, Meloxicam has demonstrated the ability to non-competitively inhibit erythrocyte PGD (6-phosphogluconate dehydrogenase) activity in vitro.Nonsteroidal anti-inflammatory drug (NSAID). Selectively inhibits COX-2 over COX-1 (IC 50 values are 4.7 and 36.3 μM respectively). Analgesic effects.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参考SDS，以获取更多信息。需要更多有关溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Meloxicam 是一种非甾体类抗炎剂，具有镇痛和降低发烧作用。An inhibitor of Cox-1 and Cox-2, selective for Cox-2.Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects.An inhibitor of Cox-1 and Cox-2, selective for Cox-2.

IUPAC Name：4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide

INCHI：InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)

InChi Key：ZRVUJXDFFKFLMG-UHFFFAOYSA-N

Canonical SMILES：CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O

Isomeric SMILES：CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O

RTECS：DL0702000

PubChem CID：54677470

UN Number：2811

Packing Group：III

Reaxy-Rn：5886369

DrugBank Ligand：DB00814

CAS Registry No.：71125-38-7

ChEMBL Ligand：CHEMBL599

Wikipedia：Meloxicam

RCSB PDB Ligand：MXM

PEP：meloxicam

DrugCentral Ligand：1676

溶解性：H2O 0.67 mg/mL (1.91 mM; 超声助溶)；DMSO 25 mg/mL (71.14 mM; 超声助溶 (<60°C)；Ethanol <1 mg/mL

敏感性：对热敏感

熔点：255°C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH412 Harmful to aquatic life with long lasting effectsH360 May damage fertility or the unborn child

预防措施声明：P273,P280,P321,P405,P501,P264,P270,P330,P203,P301+P316,P318

Class：6.1

Merck Index：5826

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