产品名称

英文名称：Maxacalcitol

同义词

CHEBI31801 、 MAXACALCITOL [INN] 、 (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol 、 (1S-(1alpha(R*),3abeta,4E(1S*,3R*,5Z),7aalpha))-4-Methyle、玛莎骨化醇

产品性质

CAS编号：103909-75-7

分子式：C26H42O4

分子量：418.62

PubChem编号：6398761

别名：玛莎骨化醇

英文别名：CHEBI31801 | MAXACALCITOL [INN] | (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol | (1S-(1alpha(R*),3abeta,4E(1S*,3R*,5Z),7aalpha))-4-Methyle

规格或纯度：97%

英文名称：Maxacalcitol

生化机理：Maxacalcitol?(22-Oxacalcitriol) is non-calcemic vitamin D3 analog and VDR ligand. Maxacalcitol(22-Oxacalcitriol)?is VDR-like Receptors. Maxacalcitol (22-Oxacalcitriol)suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Maxacalcitol exhibits similar effects to calcitriol in osteoblast-like cells. Maxacalcitol(22-Oxacalcitriol) inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid.

储存温度：避光,-20°C储存,充氩

运输条件：超低温冰袋运输

IUPAC Name：(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

INCHI：InChI=1S/C26H42O4/c1-17-20(15-21(27)16-24(17)28)9-8-19-7-6-12-26(5)22(10-11-23(19)26)18(2)30-14-13-25(3,4)29/h8-9,18,21-24,27-29H,1,6-7,10-16H2,2-5H3/b19-8+,20-9-/t18-,21+,22+,23-,24-,26+/m0/s1

InChi Key：DTXXSJZBSTYZKE-ZDQKKZTESA-N

Canonical SMILES：CC(C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C)OCCC(C)(C)O

Isomeric SMILES：C[C@@H]([C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C)OCCC(C)(C)O

PubChem CID：6398761

ChEMBL Ligand：CHEMBL333950

CAS Registry No.：103909-75-7

RCSB PDB Ligand：MCZ

DrugCentral Ligand：1638

溶解性：DMSO

敏感性：对光线敏感

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH300 Fatal if swallowedH310 Fatal in contact with skinH330 Fatal if inhaled

预防措施声明：P280,P302+P352,P321,P405,P501,P264,P260,P284,P271,P270,P304+P340,P403+P233,P362+P364,P330,P262,P320,P361+P364,P301+P316,P332+P317,P316

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