产品名称

英文名称：Src Inhibitor-1

同义词

179248-59-0、Src Kinase Inhibitor I、Src Inhibitor 1、Src I1、6,7-dimethoxy-N-(4-phenoxyphenyl)quinazolin-4-amine、Src Inhibitor-1、4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)-、Src-l1、6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine、Src I 1、CHEMBL97、6,7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉、SKI-1、Src-l1

产品性质

CAS编号：179248-59-0

分子式：C22H19N3O3

分子量：373.4

MDL号：MFCD01815300

PubChem编号：1474853

别名：6,7-二甲氧基-N-(4-苯氧基苯基)- 氨基喹唑啉|SKI-1|Src-l1

英文别名：179248-59-0|Src Kinase Inhibitor I|Src Inhibitor 1|Src I1|6,7-dimethoxy-N-(4-phenoxyphenyl)quinazolin-4-amine|Src Inhibitor-1|4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)-|Src-l1|6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine|Src I 1|CHEMBL97

规格或纯度：≥98%(HPLC)

英文名称：Src Inhibitor-1

生化机理：高效，选择性和双位Src家族酪氨酸激酶抑制剂（Src和Lck的IC 50值分别为44和88 nM）。具有细胞渗透性，可逆性和ATP竞争性。与ATP和肽结合位点相互作用。

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Src kinase inhibitor I is a 4-anilinoquinazole competitive inhibitor of Src family tryosine kinases. Src kinase inhibitor I is a dual site inhibitor, described to compete at both the ATP and peptide binding sites of the kinase.Src Inhibitor-1 may be used in Src kinase-mediated cell signaling studies.Src kinase inhibitor I is a 4-anilinoquinazole competitive inhibitor of Src family tryosine kinases. Src kinase inhibitor I is a dual site inhibitor, described to compete at both the ATP and peptide binding sites of the kinase.Src Inhibitor-1 may be used in Src kinase-mediated cell signaling studies.

IUPAC Name：6,7-dimethoxy-N-(4-phenoxyphenyl)quinazolin-4-amine

INCHI：InChI=1S/C22H19N3O3/c1-26-20-12-18-19(13-21(20)27-2)23-14-24-22(18)25-15-8-10-17(11-9-15)28-16-6-4-3-5-7-16/h3-14H,1-2H3,(H,23,24,25)

InChi Key：DMWVGXGXHPOEPT-UHFFFAOYSA-N

Canonical SMILES：COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OC4=CC=CC=C4)OC

Isomeric SMILES：COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OC4=CC=CC=C4)OC

WGK Germany：3

PubChem CID：1474853

ChEMBL Ligand：CHEMBL97771

CAS Registry No.：179248-59-0

溶解性：Soluble in DMSO (>10 mg/ml).

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH413 May cause long lasting harmful effects to aquatic lifeH302 Harmful if swallowed

预防措施声明：P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319

产品包装