产品名称

英文名称：AT7867

同义词

AT7867、857531-00-1、4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine、AT-7867、4-(4-(1H-pyrazol-4-yl)phenyl)-4-(4-chlorophenyl)piperidine、Piperidine, 4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]-、ERF7YL2CE2、pyrazole-based inhibitor 9、4-(4-chlor、4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶

产品性质

CAS编号：857531-00-1

分子式：C20H20ClN3

分子量：337.86

PubChem编号：11175137

别名：4-(4-氯苯基)-4-[4-(1H-吡唑-4-基)苯基]哌啶

英文别名：AT7867|857531-00-1|4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine|AT-7867|4-(4-(1H-pyrazol-4-yl)phenyl)-4-(4-chlorophenyl)piperidine|Piperidine, 4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]-|ERF7YL2CE2|pyrazole-based inhibitor 9|4-(4-chlor

规格或纯度：≥98%

英文名称：AT7867

生化机理：AT7867 is a potent and oral AKT and p70 S6 kinase inhibitor with an IC50 of 17 nM.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：AT7867是ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂，IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM，对AGC激酶家族以外的蛋白几乎无活性。A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3

IUPAC Name：4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine

INCHI：InChI=1S/C20H20ClN3/c21-19-7-5-18(6-8-19)20(9-11-22-12-10-20)17-3-1-15(2-4-17)16-13-23-24-14-16/h1-8,13-14,22H,9-12H2,(H,23,24)

InChi Key：LZMOSYUFVYJEPY-UHFFFAOYSA-N

Canonical SMILES：C1CNCCC1(C2=CC=C(C=C2)C3=CNN=C3)C4=CC=C(C=C4)Cl

Isomeric SMILES：C1CNCCC1(C2=CC=C(C=C2)C3=CNN=C3)C4=CC=C(C=C4)Cl

PubChem CID：11175137

溶解性：DMSO ≥66mg/mL Water <1.2mg/mL Ethanol ≥4.6mg/mL

密度：1.2

沸点：530.2 °C/760 mmHg

产品包装