产品名称

英文名称：CPTH2

同义词

CPTH2、357649-93-5、4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole、Histone Acetyltransferase Inhibitor IV, CPTH2、CHEMBL246811、CHEBI77993、4-(4-Chlorophenyl)-2-(2-cyclopentylidenehydrazineyl)thiazole、cyclopentylidene-[4-(4-chlorophenyl)thiazol-2

产品性质

CAS编号：357649-93-5

分子式：C14H14ClN3S

分子量：291.8

MDL号：MFCD02307488

PubChem编号：25193530

英文别名：CPTH2|357649-93-5|4-(4-chlorophenyl)-2-(2-cyclopentylidenehydrazinyl)thiazole|Histone Acetyltransferase Inhibitor IV, CPTH2|CHEMBL246811|CHEBI77993|4-(4-Chlorophenyl)-2-(2-cyclopentylidenehydrazineyl)thiazole|cyclopentylidene-[4-(4-chlorophenyl)thiazol-2

规格或纯度：≥98%

英文名称：CPTH2

生化机理：CPTH2 is a histone acetyltransferase (HAT) inhibitor modulating the Gcn5 network where HATs act as transcriptional coactivators. Histone acetylation plays an important role in regulating the chromatin structure and is tightly regulated by two classes of enzyme, histone acetyltransferases (HAT) and histone deacetylases (HDAC). Deregulated HAT and HDAC activity plays a role in the development of a range of cancers. Consequently, inhibitors of these enzymes have potential as anticancer agents.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：25mg卖完停产，不再备货

IUPAC Name：4-(4-chlorophenyl)-N-(cyclopentylideneamino)-1,3-thiazol-2-amine

INCHI：InChI=1S/C14H14ClN3S/c15-11-7-5-10(6-8-11)13-9-19-14(16-13)18-17-12-3-1-2-4-12/h5-9H,1-4H2,(H,16,18)

InChi Key：YYTHPXHGWSAKIZ-UHFFFAOYSA-N

Canonical SMILES：C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)Cl)C1

Isomeric SMILES：C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)Cl)C1

PubChem CID：25193530

溶解性：Soluble in DMSO >10 mg/mL

产品包装