产品名称

英文名称：FT-207 (NSC 148958)

同义词

NCGC00159418-05、NSC 148958、5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione、5-Fluoro-1-(tetrahydrofuran-2-yl)uracil、Riol、UPCMLD-DP063001、TEGAFUR [USAN]、1-(Tetrahydrofuran-2-yl)-5-fluorouracil、EINECS 241-846-2、Tegafur (JP17/USAN/INN)、5-FLUORO-1-(TETRAHYDRO-2-、替加氟

产品性质

CAS编号：17902-23-7

分子式：C8H9FN2O3

分子量：200.17

Beilstein号：24(5)6,285

EC号：241-846-2

MDL号：MFCD00012351

PubChem编号：5386

别名：替加氟

英文别名：NCGC00159418-05|NSC 148958|5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione|5-Fluoro-1-(tetrahydrofuran-2-yl)uracil|Riol|UPCMLD-DP063001|TEGAFUR [USAN]|1-(Tetrahydrofuran-2-yl)-5-fluorouracil|EINECS 241-846-2|Tegafur (JP17/USAN/INN)|5-FLUORO-1-(TETRAHYDRO-2-

规格或纯度：≥98% (HPLC)

英文名称：FT-207 (NSC 148958)

生化机理：Tegafur is a pro-drμg of 5-fluorouracil, an antimetabolite used as an antineoplastic agent. It has been used as adjuvant chemotherapy for curatively resected colorectal cancer therapy.Prodrug, metabolized to 5-fluorouracil. Antimetabolite and antineoplastic agent. Orally active. Active in vivo and in vitro .

应用：A congener of fluorouracil.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Tegafur (FT-207, NSC 148958)用于治疗某些类型的癌症。A congener of fluorouracil.Tegafur (FT-207, NSC 148958) is a substance being used in the treatment of some types of cancer.A congener of fluorouracil.

ALogP：-0.3

IUPAC Name：5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione

INCHI：InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13)

InChi Key：WFWLQNSHRPWKFK-UHFFFAOYSA-N

Canonical SMILES：C1CC(OC1)N2C=C(C(=O)NC2=O)F

Isomeric SMILES：C1CC(OC1)N2C=C(C(=O)NC2=O)F

WGK Germany：3

RTECS：YR0450000

关联CAS：17902-23-7,82294-77-7

PubChem CID：5386

MeSH Entry Terms：1-(2-Tetrahydrofuryl)-5-fluorouracil;1-(Tetrahydro-2-furanyl)-5-fluorouracil;5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione;Florafur;Fluorofur;FT 207;FT-207;FT207;Ftorafur;Futraful;N1-(2'-Tetrahydrofuryl)-5-fluorouracil;Sunfural S;Tegafur;Uftoral;U

Reaxy-Rn：525766

CAS Registry No.：17902-23-7

ChEMBL Ligand：CHEMBL20883

DrugCentral Ligand：4398

溶解性：Soluble in DMSO (>50 mg/ml at 25 °C), water (8 mg/ml at 25 °C), and ethanol (7 mg/ml at 25 °C).

熔点：171-173°C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH311 Toxic in contact with skinH331 Toxic if inhaled

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P330,P361+P364,P301+P316,P316

Merck Index：9112

产品包装