产品名称

英文名称：ProcyanidinB2

同义词

BDBM50553253、P17914、AKOS008901339、Proanthocyanidin B2、PROCYANIDIN B2, (+)-、(2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-2H,2'H-4,8'-bichromene-3,3',5,5',7,7'-hexol、(4,8'-BI-2H-1-BENZOPYRAN)-3,3',5,5',7,7'-HEXOL, 2,2'-BIS(3,4-DIHYD、原花青素 B2

产品性质

CAS编号：29106-49-8

分子式：C30H26O12

分子量：578.52

MDL号：MFCD01861513

PubChem编号：122738

别名：原花青素 B2

英文别名：BDBM50553253|P17914|AKOS008901339|Proanthocyanidin B2|PROCYANIDIN B2, (+)-|(2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-2H,2'H-4,8'-bichromene-3,3',5,5',7,7'-hexol|(4,8'-BI-2H-1-BENZOPYRAN)-3,3',5,5',7,7'-HEXOL, 2,2'-BIS(3,4-DIHYD

规格或纯度：≥90%

英文名称：ProcyanidinB2

生化机理：Procyanidin B2 exerts a potent and beneficial role in reducing granulosa cell apoptosis and inducing autophagy process,and exerts a variety of potent protective pharmacological effects on diabetic complications. In vitro Procyanidin B2 treatment decreased FoxO1 protein level, improved granulosa cell viability, upregulated LC3-II protein level, and reduced granulosa cell apoptosis rate. Under a condition of oxidative stress, Procyanidin B2 reversed FoxO1 nuclear localization and increased its level in cytoplasm. In addition, FoxO1 knockdown inhibited the protective effects of Procyanidin B2 induced.

应用：Procyanidin B2能够诱导自噬，减少颗粒细胞凋亡,并且对能够降低糖尿病并发症的发生。

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

备注：卖完停产，不再备货

产品介绍：Procyanidin B2能够诱导自噬，减少颗粒细胞凋亡,并且对能够降低糖尿病并发症的发生。Procyanidin B2 exerts a potent and beneficial role in reducing granulosa cell apoptosis and inducing autophagy process,and exerts a variety of potent protective pharmacological effects on diabetic complications.

IUPAC Name：(2R,3R)-2-(3,4-dihydroxyphenyl)-8-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol

INCHI：InChI=1S/C30H26O12/c31-13-7-20(37)24-23(8-13)41-29(12-2-4-16(33)19(36)6-12)27(40)26(24)25-21(38)10-17(34)14-9-22(39)28(42-30(14)25)11-1-3-15(32)18(35)5-11/h1-8,10,22,26-29,31-40H,9H2/t22-,26-,27-,28-,29-/m1/s1

InChi Key：XFZJEEAOWLFHDH-NFJBMHMQSA-N

Canonical SMILES：C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O

Isomeric SMILES：C1[C@H]([C@H](OC2=C1C(=CC(=C2[C@@H]3[C@H]([C@H](OC4=CC(=CC(=C34)O)O)C5=CC(=C(C=C5)O)O)O)O)O)C6=CC(=C(C=C6)O)O)O

PubChem CID：122738

折光率：1.8

沸点：955.32° C

熔点：197-198°C

产品包装