产品名称

英文名称：Vilazodone

同义词

5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperazin-1-yl)-1-benzofuran-2-carboxamide、EMD 515259、2,5-bis(p-aminophenyl)-1,3,4-oxadiazole、NCGC00371130-06、VILAZODONE [VANDF]、EINECS 219-401-9、N06AX24、SGEGOXDYSFKCPT-UHFFFAOYSA-N、NCGC00371130-03、VILAZODONE [WHO-DD]、维拉佐酮

产品性质

CAS编号：163521-12-8

分子式：C26H27N5O2

分子量：441.52

PubChem编号：6918314

别名：维拉佐酮

英文别名：5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)piperazin-1-yl)-1-benzofuran-2-carboxamide|EMD 515259|2,5-bis(p-aminophenyl)-1,3,4-oxadiazole|NCGC00371130-06|VILAZODONE [VANDF]|EINECS 219-401-9|N06AX24|SGEGOXDYSFKCPT-UHFFFAOYSA-N|NCGC00371130-03|VILAZODONE [WHO-DD]|

规格或纯度：≥98%

英文名称：Vilazodone

生化机理：Vilazodone (EMD 68843; SB 659746A; 5-{4-[4-(5-cyano-3-indolyl)-butyl]-1-piperazinyl}-benzofuran-2-carboxamide hydrochloride) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Vilazodone is an inhibitor of ST (serotonin transporter and uptake) (IC50 = 0.5 nM) and SR-1A activator (partial agonist) (IC50 = 0.2 nM; IA = ~60-70%).An inhibitor of ST and activator of SR-1AVilazodone is an inhibitor of ST (serotonin transporter and uptake) (IC50 = 0.5 nM) and SR-1A activator (partial agonist) (IC50 = 0.2 nM; IA = ~60-70%).An inhibitor of ST and activator of SR-1A

IUPAC Name：5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide

INCHI：InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32)

InChi Key：SGEGOXDYSFKCPT-UHFFFAOYSA-N

Canonical SMILES：C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N

Isomeric SMILES：C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N

PubChem CID：6918314

ChEMBL Ligand：CHEMBL439849

CAS Registry No.：163521-12-8

DrugBank Ligand：DB06684

Wikipedia：Vilazodone

PEP：vilazodone

RCSB PDB Ligand：YG7

DrugCentral Ligand：4223

GPCRdb Ligand：vilazodone

溶解性：DMSO

产品包装