产品名称

英文名称：SRT1720 HCl

同义词

1001645-58-4、SRT1720、SRT 1720 Hydrochloride、SRT1720 HCl、SRT 1720 (Hydrochloride)、SRT1720 xHydrochloride、N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide hydrochloride、N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thia、N-[2-[3-(1-哌嗪甲基)咪唑并[2,1-b]噻唑-6-基]苯基]-2-喹喔啉甲酰胺盐酸盐

产品性质

CAS编号：1001645-58-4

分子式：C25H23N7OS.HCl

分子量：506.02

PubChem编号：25232708

别名：N-[2-[3-(1-哌嗪甲基)咪唑并[2,1-b]噻唑-6-基]苯基]-2-喹喔啉甲酰胺盐酸盐

英文别名：1001645-58-4|SRT1720|SRT 1720 Hydrochloride|SRT1720 HCl|SRT 1720 (Hydrochloride)|SRT1720 xHydrochloride|N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)quinoxaline-2-carboxamide hydrochloride|N-[2-[3-(1-Piperazinylmethyl)imidazo[2,1-b]thia

规格或纯度：≥98%

英文名称：SRT1720 HCl

生化机理：SRT1720 is an NAD-dependent deacetylase sirtuin-1 (SIRT1) activator (EC50 = 0.16 μM), highly selective for SIRT1 over SIRT2 or SIRT3. Studies in yeast sμggest that sirtuins may be involved in epigentic gene silencing and deactylation of proteins that regulate the cell cycle.Selective SIRT1 activator (EC 50 = 0.16 μM), 230-fold less potent for SIRT2 and SIRT3. Induce autophagy.

储存温度：-20°C储存

运输条件：超低温冰袋运输

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产品介绍：SRT1720是一种选择性的SIRT1激活剂，EC50为0.16 μM，比作用于SIRT2和SIRT3效果弱230倍以上。A selective SIRT1 activatorSRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3.A selective SIRT1 activator

IUPAC Name：N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide;hydrochloride

INCHI：InChI=1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31;/h1-8,13,15-16,26H,9-12,14H2,(H,29,33);1H

InChi Key：DTGRRMPPXCRRIM-UHFFFAOYSA-N

Canonical SMILES：C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl

Isomeric SMILES：C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl

PubChem CID：25232708

溶解性：DMSO 38 mg/mL Water <1 mg/mL Ethanol <1 mg/mL

产品包装