产品名称

英文名称：R(+) -Verapamil monohydrochloride

同义词

AKOS040736385 、 UNII-B0P742MK5O 、 CARPRONIUM CHLORIDE [WHO-DD] 、 CHEBI77739 、 BENZENEACETONITRILE, .ALPHA.-(3-((2-(3,4-DIMETHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-3,4-DIMETHOXY-.ALPHA.-(1-METHYLETHYL)-, MONOHYDROCHLORIDE, (.ALPHA.R)- 、 B0P742MK5O 、 VERAPAM、盐酸维拉帕米杂质22

产品性质

CAS编号：38176-02-2

分子式：C27H39ClN2O4

分子量：491.06

PubChem编号：170014

别名：盐酸维拉帕米杂质22

英文别名：AKOS040736385 | UNII-B0P742MK5O | CARPRONIUM CHLORIDE [WHO-DD] | CHEBI77739 | BENZENEACETONITRILE, .ALPHA.-(3-((2-(3,4-DIMETHOXYPHENYL)ETHYL)METHYLAMINO)PROPYL)-3,4-DIMETHOXY-.ALPHA.-(1-METHYLETHYL)-, MONOHYDROCHLORIDE, (.ALPHA.R)- | B0P742MK5O | VERAPAM

规格或纯度：95%

英文名称：R(+) -Verapamil monohydrochloride

生化机理：Verapamil is a calcium channel blocker.Verapamil hydrochloride is a phenyl-alkyl amine derivative and is potentially used for treating hypertension, angina pectoris and arrhythmias. It is water soluble in nature. Inhibitor of P-glycoprotein; less active enantiomer of (±)-verapamil.

储存温度：室温,充氩

运输条件：常规运输

产品介绍：ApplicationR(+)-Verapamil monohydrochloride has been used as a P-glycoprotein (gp) inhibitor, to detect P-gp expression on the SK-OV-3 and SK-OV-3/DDP cell surface by flow cytometry. It has also been used as a calcium channel blocker, to evaluate its effect on doxorubicin (DOX) cytotoxicity

IUPAC Name：(2R)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride

INCHI：InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H/t27-;/m1./s1

InChi Key：DOQPXTMNIUCOSY-HZPIKELBSA-N

Canonical SMILES：CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl

Isomeric SMILES：CC(C)[C@@](CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl

PubChem CID：170014

溶解性：H2O >30 mg/mL；ethanol soluble

敏感性：对湿度敏感

产品包装