产品名称

英文名称：Doramectin

同义词

Doramectina 、 Doramectine [INN-French] 、 Doramectina [INN-Spanish] 、 Doramectin 、 Doramectine 、 Doramectinum 、 Dectomax 、 Doramectinum [INN-Latin]

产品性质

CAS编号：117704-25-3

分子式：C50H74O14

分子量：899.11

MDL号：MFCD00894747

PubChem编号：9832750

英文别名：Doramectina | Doramectine [INN-French] | Doramectina [INN-Spanish] | Doramectin | Doramectine | Doramectinum | Dectomax | Doramectinum [INN-Latin]

规格或纯度：98%

英文名称：Doramectin

生化机理：Doramectin is a derivative of ivermectin. It is thoμght to work like other macrocyclic lactones by opening glutamate-gated chloride channels in the nerve cells, causing paralysis.

储存温度：2-8°C储存,避光

运输条件：冰袋运输

产品介绍：Doramectin 是 Ivermectin (HY-15310) 的衍生物。Doramectin 是一种有效的抗寄生虫抗生素。Doramectin 具有在 NMRI 小鼠感染模型中抗曼氏链球菌作用。Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model.

IUPAC Name：(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-cyclohexyl-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one

INCHI：InChI=1S/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,29,31-33,35-47,51-52,54H,9-11,14-15,18,22-26H2,1-8H3/b13-12+,28-17+,34-16+/t27-,29-,31-,32-,35+,36-,37-,38-,39-,40-,41-,42+,43-,44-,45-,46-,47+,49+,50+/m0/s1

InChi Key：QLFZZSKTJWDQOS-YDBLARSUSA-N

Canonical SMILES：CC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)O)OC)OC)C)OC7(C4)C=CC(C(O7)C8CCCCC8)C)O

Isomeric SMILES：C[C@H]1/C=C/C=C/2\CO[C@H]3[C@@]2([C@@H](C=C([C@H]3O)C)C(=O)O[C@H]4C[C@@H](C/C=C(/[C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)OC)\C)O[C@]7(C4)C=C[C@@H]([C@H](O7)C8CCCCC8)C)O

WGK Germany：3

PubChem CID：9832750

溶解性：Soluble in water (partly), chloroform, and methanol., Soluble in water (partly), chloroform, and methanol.

敏感性：对热敏感;对光线敏感

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH302 Harmful if swallowedH400 Very toxic to aquatic lifeH410 Very toxic to aquatic life with long lasting effectsH300 Fatal if swallowedH372 Causes damage to organs through prolonged or repeated exposureH360 May damage fertility or the unborn childH370 Causes damage to organsH361 Suspected of damaging fertility or the unborn childH362 May cause harm to breast-fed children

预防措施声明：P273,P280,P321,P405,P501,P264,P260,P270,P391,P330,P263,P203,P301+P316,P301+P317,P318,P308+P316,P319

个人防护装备：Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

产品包装