产品名称

英文名称：BMS-690514

同义词

BMS-690514、859853-30-8、(3R,4R)-4-Amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-3-ol、BMS 690514、VKU5X213Q7、Bms 6690514、(3R,4R)-4-Amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo-[2,1-f][1,2,4]triazin-5-yl]methyl]piperidi

产品性质

CAS编号：859853-30-8

分子式：C19H24N6O2

分子量：368.44

PubChem编号：11349170

英文别名：BMS-690514|859853-30-8|(3R,4R)-4-Amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-3-ol|BMS 690514|VKU5X213Q7|Bms 6690514|(3R,4R)-4-Amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo-[2,1-f][1,2,4]triazin-5-yl]methyl]piperidi

规格或纯度：≥99%

英文名称：BMS-690514

生化机理：BMS-690514 is a potent and selective inhibitor of epidermal growth factor receptor (EGFR), HER2, and HER4, as well as the VEGF receptor kinases. BMS-690514 inhibits proliferation of tumor cells with potency that correlates with inhibition of receptor signaling, and induces apoptosis in lung tumor cells that have an activating mutation in EGFR.

储存温度：-20°C储存

运输条件：超低温冰袋运输

ALogP：0.7

IUPAC Name：(3R,4R)-4-amino-1-[[4-(3-methoxyanilino)pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-3-ol

INCHI：InChI=1S/C19H24N6O2/c1-27-15-4-2-3-14(9-15)23-19-18-13(5-8-25(18)22-12-21-19)10-24-7-6-16(20)17(26)11-24/h2-5,8-9,12,16-17,26H,6-7,10-11,20H2,1H3,(H,21,22,23)/t16-,17-/m1/s1

InChi Key：CSGQVNMSRKWUSH-IAGOWNOFSA-N

Canonical SMILES：COC1=CC=CC(=C1)NC2=NC=NN3C2=C(C=C3)CN4CCC(C(C4)O)N

Isomeric SMILES：COC1=CC=CC(=C1)NC2=NC=NN3C2=C(C=C3)CN4CC[C@H]([C@@H](C4)O)N

PubChem CID：11349170

CAS Registry No.：859853-30-8

溶解性：DMSO

产品包装