产品名称

英文名称：OSI-027

同义词

OSI-027、936890-98-1、OSI027、OSI 027、25MKH1SZ0M、AEVI-006、CERC-006、ASP-7486、936890-98-1 (free acid)、4-[(5Z)-4-amino-5-(7-methoxyindol-2-ylidene)-1H-imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic acid、Cyclohexanecarboxylic acid, 4-(4-amino-5-(7-me

产品性质

CAS编号：936890-98-1

分子式：C21H22N6O3

分子量：406.45

PubChem编号：135398516

英文别名：OSI-027|936890-98-1|OSI027|OSI 027|25MKH1SZ0M|AEVI-006|CERC-006|ASP-7486|936890-98-1 (free acid)|4-[(5Z)-4-amino-5-(7-methoxyindol-2-ylidene)-1H-imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic acid|Cyclohexanecarboxylic acid, 4-(4-amino-5-(7-me

规格或纯度：95%

英文名称：OSI-027

生化机理：OSI-027 is a potent mammalian target of rapamycin (mTOR) kinase inhibitor.Potent, ATP-competitive mTOR kinase inhibitor. Inhibits TORC1 (IC 50 = 22 nM) and TORC2 (IC 50 = 65 nM) mTor complexes. Greater than 100-fold selective for mTOR versus PI3K-alpha, PI3K-beta, PI3K-gamma and DNA-PK.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：有关更多信息，请参阅SDS。有关溶解度，用法和处理的更多建议？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

ALogP：2

IUPAC Name：4-[4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]cyclohexane-1-carboxylic acid

INCHI：InChI=1S/C21H22N6O3/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29/h2-4,9-12,25H,5-8H2,1H3,(H,28,29)(H2,22,23,24)

InChi Key：JROFGZPOBKIAEW-UHFFFAOYSA-N

Canonical SMILES：COC1=CC=CC2=C1NC(=C2)C3=C4C(=NC=NN4C(=N3)C5CCC(CC5)C(=O)O)N

Isomeric SMILES：COC1=CC=CC2=C1NC(=C2)C3=C4C(=NC=NN4C(=N3)C5CCC(CC5)C(=O)O)N

PubChem CID：135398516

溶解性：DMSO 18 mg/mL Water <1 mg/mL Ethanol <1 mg/mL

产品包装