产品名称

英文名称：MI-2

同义词

1271738-62-5、MI-2、4-(4-(5,5-Dimethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-propylthieno[2,3-d]pyrimidine、4-[4-(5,5-dimethyl-4H-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-d]pyrimidine、Menin-MLL Inhibitor 2、Menin-MLL inhibitor MI-2、MI 2 (Menin-、4-[4-(4,5-二氢-5,5-二甲基-2-噻唑基)-1-哌嗪基]-6-丙基噻吩并[2,3-d]嘧啶

产品性质

CAS编号：1271738-62-5

分子式：C18H25N5S2

分子量：375.55

PubChem编号：54765302

别名：4-[4-(4,5-二氢-5,5-二甲基-2-噻唑基)-1-哌嗪基]-6-丙基噻吩并[2,3-d]嘧啶

英文别名：1271738-62-5|MI-2|4-(4-(5,5-Dimethyl-4,5-dihydrothiazol-2-yl)piperazin-1-yl)-6-propylthieno[2,3-d]pyrimidine|4-[4-(5,5-dimethyl-4H-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-d]pyrimidine|Menin-MLL Inhibitor 2|Menin-MLL inhibitor MI-2|MI 2 (Menin-

规格或纯度：≥98%

英文名称：MI-2

生化机理：MI-2 is Menin-MLL inhibitor, inhibitors of the menin-MLL fusion protein interaction that specifically bind menin with nanomolar affinities.Menin-MLL (Mixed linage leukemia) protein interaction inhibitor (IC 50 = 0.45\xa0μM).\xa0\xa0Selectively inhibits proliferation and induces apoptosis of leukemia cells harboring MLL fusion proteins. Blocks transformation and induces hematopoietic differen

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：有关更多信息，请参考SDS。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：MI-2是Menin-MLL相互作用抑制剂，IC50为446 nM。MI-2 (Menin-MLL Inhibitor) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.

IUPAC Name：4-[4-(5,5-dimethyl-4H-1,3-thiazol-2-yl)piperazin-1-yl]-6-propylthieno[2,3-d]pyrimidine

INCHI：InChI=1S/C18H25N5S2/c1-4-5-13-10-14-15(20-12-21-16(14)24-13)22-6-8-23(9-7-22)17-19-11-18(2,3)25-17/h10,12H,4-9,11H2,1-3H3

InChi Key：SRQYLNYQAPCPIR-UHFFFAOYSA-N

Canonical SMILES：CCCC1=CC2=C(N=CN=C2S1)N3CCN(CC3)C4=NCC(S4)(C)C

Isomeric SMILES：CCCC1=CC2=C(N=CN=C2S1)N3CCN(CC3)C4=NCC(S4)(C)C

PubChem CID：54765302

溶解性：DMSO

产品包装