产品名称

英文名称：XTT sodium salt

同义词

2,3-双(2-甲氧基-4-硝基-5-磺苯基)-2H-四唑-5-甲酰胺内盐 、 4-甲氧基-5-[3-(2-甲氧基-4-硝基-5-磺酸基苯基)-5-(苯基氨基甲酰基)四唑-3-鎓-2-基]-2-硝基苯磺酸钠

产品性质

CAS编号：111072-31-2

分子式：C22H16N7NaO13S2

分子量：673.52

MDL号：MFCD00083517

PubChem编号：14195569

别名：2,3-双(2-甲氧基-4-硝基-5-磺苯基)-2H-四唑-5-甲酰胺内盐 | 4-甲氧基-5-[3-(2-甲氧基-4-硝基-5-磺酸基苯基)-5-(苯基氨基甲酰基)四唑-3-鎓-2-基]-2-硝基苯磺酸钠

规格或纯度：90%

英文名称：XTT sodium salt

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

产品介绍：XTT sodium salt is a tetrazolium sodium salt that can be used in the XTT assay for cell viablilty and cell proliferation. The reactions involving XTT sodium salt will result in the formation of a soluble formazan dye, an advantage over the use of MTT due to MTT requiring a solubilization step. another advantage of XTT sodium salt is higher sensitivity and greater dynamic range over MTT. XTT sodium salt has displayed applicability in monitoring biologcially active products with superoxide anion participation in DNA scission. The compound has also been used to asses valvular injury for testing cryopreserved cardiac valves.用于艾滋病和癌症测试。 XTT has been used in conjunction with phenazine methosulfate (PMS) to screen human cancer cell lines.1 The tetrazolium dye has also been used to study fungal cell damage, in testing antimicrobial susceptibility of staphylococci, and in Candida biofilm research. Limitations to the XTT assay have been reported.XTT sodium salt is a tetrazolium sodium salt that can be used in the XTT assay for cell viablilty and cell proliferation. The reactions involving XTT sodium salt will result in the formation of a soluble formazan dye, an advantage over the use of MTT due to MTT requiring a solubilization step. another advantage of XTT sodium salt is higher sensitivity and greater dynamic range over MTT. XTT sodium salt has displayed applicability in monitoring biologcially active products with superoxide anion participation in DNA scission. The compound has also been used to asses valvular injury for testing cryopreserved cardiac valves.Useful in AIDS and cancer testing XTT sodium salt is a tetrazolium sodium salt that can be used in the XTT assay for cell viablilty and cell proliferation. The reactions involving XTT sodium salt will result in the formation of a soluble formazan dye, an advantage over the use of MTT due to MTT requiring a solubilization step. another advantage of XTT sodium salt is higher sensitivity and greater dynamic range over MTT. XTT sodium salt has displayed applicability in monitoring biologcially active products with superoxide anion participation in DNA scission. The compound has also been used to asses valvular injury for testing cryopreserved cardiac valves.

IUPAC Name：sodium;4-methoxy-5-[3-(2-methoxy-4-nitro-5-sulfonatophenyl)-5-(phenylcarbamoyl)tetrazol-3-ium-2-yl]-2-nitrobenzenesulfonate

INCHI：InChI=1S/C22H17N7O13S2.Na/c1-41-17-8-15(28(31)32)19(43(35,36)37)10-13(17)26-24-21(22(30)23-12-6-4-3-5-7-12)25-27(26)14-11-20(44(38,39)40)16(29(33)34)9-18(14)42-2;/h3-11H,1-2H3,(H2-,23,30,35,36,37,38,39,40);/q;+1/p-1

InChi Key：JACYMBNQPPWQML-UHFFFAOYSA-M

Canonical SMILES：COC1=CC(=C(C=C1N2N=C(N=[N+]2C3=CC(=C(C=C3OC)[N+](=O)[O-])S(=O)(=O)[O-])C(=O)NC4=CC=CC=C4)S(=O)(=O)[O-])[N+](=O)[O-].[Na+]

Isomeric SMILES：COC1=CC(=C(C=C1N2N=C(N=[N+]2C3=CC(=C(C=C3OC)[N+](=O)[O-])S(=O)(=O)[O-])C(=O)NC4=CC=CC=C4)S(=O)(=O)[O-])[N+](=O)[O-].[Na+]

WGK Germany：3

PubChem CID：14195569

溶解性：Soluble in hot water at 2.5mg/ml.Soluble in water, dimethyl sulfoxide, dimethyl formamide and phosphate buffered saline.at pH =7.2.

敏感性：对湿度敏感

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装