产品名称

英文名称：INCB3344

同义词

INCB3344、709018-37-1、1262238-11-8、N-(2-(((3S,4S)-1-(4-(Benzo[d][1,3]dioxol-5-yl)-4-hydroxycyclohexyl)-4-ethoxypyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide、1285539-85-6、INCB3344 R-isomer、CID 10008367、cis-INCB3344、Benzamide, N-[2-[[(3R,4R

产品性质

CAS编号：1262238-11-8

分子式：C29H34F3N3O6

分子量：577.24

PubChem编号：10008367

英文别名：INCB3344|709018-37-1|1262238-11-8|N-(2-(((3S,4S)-1-(4-(Benzo[d][1,3]dioxol-5-yl)-4-hydroxycyclohexyl)-4-ethoxypyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide|1285539-85-6|INCB3344 R-isomer|CID 10008367|cis-INCB3344|Benzamide, N-[2-[[(3R,4R

规格或纯度：≥99%

英文名称：INCB3344

生化机理：INCB3344 is a potent and selective small molecule CCR2 chemokine receptor antagonist. INCB3344 is useful for anti chronic inflammatory diseases

储存温度：-20°C储存

运输条件：超低温冰袋运输

IUPAC Name：N-[2-[[(3S,4S)-1-[4-(1,3-benzodioxol-5-yl)-4-hydroxycyclohexyl]-4-ethoxypyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide

INCHI：InChI=1S/C29H34F3N3O6/c1-2-39-25-16-35(21-8-10-28(38,11-9-21)19-6-7-23-24(13-19)41-17-40-23)15-22(25)34-26(36)14-33-27(37)18-4-3-5-20(12-18)29(30,31)32/h3-7,12-13,21-22,25,38H,2,8-11,14-17H2,1H3,(H,33,37)(H,34,36)/t21?,22-,25-,28?/m0/s1

InChi Key：MZEOSVPWMSEFPW-XYCDVDSTSA-N

Canonical SMILES：CCOC1CN(CC1NC(=O)CNC(=O)C2=CC(=CC=C2)C(F)(F)F)C3CCC(CC3)(C4=CC5=C(C=C4)OCO5)O

Isomeric SMILES：CCO[C@H]1CN(C[C@@H]1NC(=O)CNC(=O)C2=CC(=CC=C2)C(F)(F)F)C3CCC(CC3)(C4=CC5=C(C=C4)OCO5)O

PubChem CID：10008367

BindingDB Ligand：50331728

CAS Registry No.：1262238-11-8

ChEMBL Ligand：CHEMBL2426341

GPCRdb Ligand：INCB3344

溶解性：DMSO

产品包装