产品名称

英文名称：Cebranopadol

同义词

Cebranopadol、863513-91-1、GRT6005、GRT-6005、GRT 6005、863513-93-3、Cebranopadol ((1alpha,4alpha)stereoisomer)、Cebranopadol(GRT-6005)、7GDW9S3GN3、863513-91-1 (free base)、(1r,4r)-6'-Fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4

产品性质

CAS编号：863513-91-1

分子式：C24H27FN2O

分子量：378.48

PubChem编号：11848225

英文别名：Cebranopadol|863513-91-1|GRT6005|GRT-6005|GRT 6005|863513-93-3|Cebranopadol ((1alpha,4alpha)stereoisomer)|Cebranopadol(GRT-6005)|7GDW9S3GN3|863513-91-1 (free base)|(1r,4r)-6'-Fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4

规格或纯度：≥98%

英文名称：Cebranopadol

生化机理：DescriptionIC50 Value N/ACebranopadol and GRT 6006 are novel first-in-class compounds with unique pharmacological and pharmacokinetic profiles that may enhance their effect in certain pain conditions. The unique mode of action of these compounds builds on the ORL-1 receptor and, supported by the established mu opioid receptor, is particularly suitable for the treatment of moderate to severe chronic pain [1].in vitro N/Ain vivo N/AClinical trial Cebranopadol has successfully completed initial proof-of-concept studies in nociceptive and neuropathic pain with further Phase II studies planned prior to initiation of Phase III studies.

储存温度：-20°C储存

运输条件：超低温冰袋运输

IUPAC Name：6-fluoro-N,N-dimethyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine

INCHI：InChI=1S/C24H27FN2O/c1-27(2)23(17-6-4-3-5-7-17)11-13-24(14-12-23)22-19(10-15-28-24)20-16-18(25)8-9-21(20)26-22/h3-9,16,26H,10-15H2,1-2H3

InChi Key：CSMVOZKEWSOFER-UHFFFAOYSA-N

Canonical SMILES：CN(C)C1(CCC2(CC1)C3=C(CCO2)C4=C(N3)C=CC(=C4)F)C5=CC=CC=C5

Isomeric SMILES：CN(C)C1(CCC2(CC1)C3=C(CCO2)C4=C(N3)C=CC(=C4)F)C5=CC=CC=C5

PubChem CID：11848225

ChEMBL Ligand：CHEMBL2364605

CAS Registry No.：863513-91-1

Wikipedia：Cebranopadol

GPCRdb Ligand：cebranopadol

溶解性：DMSO

产品包装