产品名称

英文名称：Closantel

同义词

Closantel、57808-65-8、N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide、NSC-335306、R 31,520、CHEMBL12131、Benzamide, N-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-diiodo-、MLS001332593、EUL5、氯氰碘柳胺、氯生太尔

产品性质

CAS编号：57808-65-8

分子式：C22H14Cl2I2N2O2

分子量：663.07

EC号：260-967-1

MDL号：MFCD00661151

PubChem编号：42574

别名：氯氰碘柳胺|氯生太尔

英文别名：Closantel|57808-65-8|N-(5-chloro-4-((4-chlorophenyl)(cyano)methyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide|NSC-335306|R 31,520|CHEMBL12131|Benzamide, N-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-diiodo-|MLS001332593|EUL5

规格或纯度：≥98%

英文名称：Closantel

生化机理：Closantel is an antihelmintic agent and a potentially useful compound for studying P-glycoprotein interactions in vitro.Antibacterial and antiparasitic agent. Inhibits the KinA/Spo0F system (IC 50 = 3.8 μM). Shows activity against Gram-positive bacteria and shows antiparasitic effects in vivo.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：50mg卖完停产，不再备货。如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Closantel是革兰氏阳性的抗菌活性抑制剂，抑制KinA/Spo0F系统，IC50为3.8 μM。Potentially useful for studying P-glycoprotein interactions in vitro.Closantel is a gram positive antibacterial activity inhibitor, inhibiting the KinA/Spo0F system with IC50 of 3.8 μM.Potentially useful for studying P-glycoprotein interactions in vitro.

IUPAC Name：N-[5-chloro-4-[(4-chlorophenyl)-cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamide

INCHI：InChI=1S/C22H14Cl2I2N2O2/c1-11-6-15(17(10-27)12-2-4-13(23)5-3-12)18(24)9-20(11)28-22(30)16-7-14(25)8-19(26)21(16)29/h2-9,17,29H,1H3,(H,28,30)

InChi Key：JMPFSEBWVLAJKM-UHFFFAOYSA-N

Canonical SMILES：CC1=CC(=C(C=C1NC(=O)C2=C(C(=CC(=C2)I)I)O)Cl)C(C#N)C3=CC=C(C=C3)Cl

Isomeric SMILES：CC1=CC(=C(C=C1NC(=O)C2=C(C(=CC(=C2)I)I)O)Cl)C(C#N)C3=CC=C(C=C3)Cl

WGK Germany：3

RTECS：CV2444250

PubChem CID：42574

溶解性：Insoluble in water.

熔点：218-223°C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH413 May cause long lasting harmful effects to aquatic life

预防措施声明：P273,P321,P405,P501,P264,P270,P330,P301+P316

个人防护装备：dust mask type N95 (US), Eyeshields, Faceshields, Gloves

产品包装