产品名称

英文名称：Catharanthine

同义词

7-Ethyl-9,10,12,13-tetrahydro-6,9-methano-5H-pyrido[1',2'1,2]azepino[4,5-b]indole-6(6aH)-carboxylic acid methyl ester 、 (+)-3,4-Didehydrocoronaridine、(2α,5β,6α,18β)-3,4-Didehydroibogamine-18-carboxylic acid methyl ester 、 泻花碱

产品性质

CAS编号：2468-21-5

分子式：C21H24N2O2

分子量：336.43

MDL号：MFCD01753356

PubChem编号：5458190

别名：(2α,5β,6α,18β)-3,4-Didehydroibogamine-18-carboxylic acid methyl ester | 泻花碱

英文别名：7-Ethyl-9,10,12,13-tetrahydro-6,9-methano-5H-pyrido[1',2'1,2]azepino[4,5-b]indole-6(6aH)-carboxylic acid methyl ester | (+)-3,4-Didehydrocoronaridine

规格或纯度：分析标准品,≥98%

英文名称：Catharanthine

生化机理：Catharanthine is a precursor of the anti-tumor drμgs vinblastine and vincristine, formed by dimerization of catharanthine with vindoline. Catharanthine itself is an inhibitor of tubulin self-assembly into microtubules, althoμgh not so potent as vinblastine or vincristine. Catharanthine also has anticholinergic activity. It showed muscarinic antagonism at 10 microM and fully inhibited nicotinic receptor mediated diaphragm contractions with an IC50 of 59.6 microM.Monomeric precursor to Vincristine and vinblastine . Weakly affects bipolar mitotic spindle formation. Shows weak tubulin polymerization inhibition and weak cytotoxic effects.

储存温度：避光,-20°C储存,充氩

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

IUPAC Name：methyl (1R,15R,18R)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8,16-pentaene-1-carboxylate

INCHI：InChI=1S/C21H24N2O2/c1-3-14-10-13-11-21(20(24)25-2)18-16(8-9-23(12-13)19(14)21)15-6-4-5-7-17(15)22-18/h4-7,10,13,19,22H,3,8-9,11-12H2,1-2H3/t13-,19+,21-/m0/s1

InChi Key：CMKFQVZJOWHHDV-NQZBTDCJSA-N

Canonical SMILES：CCC1=CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC

Isomeric SMILES：CCC1=C[C@H]2C[C@]3([C@@H]1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC

WGK Germany：3

PubChem CID：5458190

密度：1.27

敏感性：对光线敏感；对空气敏感

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

产品包装