产品名称

英文名称：Prostaglandin E1

同义词

alprostadil、Prostaglandin E1、745-65-3、PGE1、Edex、Caverject、Muse、Prostin VR、Prostavasin、Befar、Alprostadilum、Femprox、Topiglan、Alprox-TD、Liprostin、Prostandin、l-Prostaglandin E1、Vitaros、Prink、Prostin VR Pediatric、PGE-1、Lipoprost、Promostan、Prostivas、Caverject I、前列地尔、(11α,13E,15S)-11,15-二羟基-9-氧代前列-13-烯-1-酸

产品性质

CAS编号：745-65-3

分子式：C20H34O5

分子量：354.48

Beilstein号：5294062

EC号：212-017-2

MDL号：MFCD00077860

PubChem编号：5280723

别名：前列地尔|(11α,13E,15S)-11,15-二羟基-9-氧代前列-13-烯-1-酸

英文别名：alprostadil|Prostaglandin E1|745-65-3|PGE1|Edex|Caverject|Muse|Prostin VR|Prostavasin|Befar|Alprostadilum|Femprox|Topiglan|Alprox-TD|Liprostin|Prostandin|l-Prostaglandin E1|Vitaros|Prink|Prostin VR Pediatric|PGE-1|Lipoprost|Promostan|Prostivas|Caverject I

规格或纯度：≥98%(HPLC)

英文名称：Prostaglandin E1

生化机理：前列腺素对EP3和EP4受体具有一定的选择性（小鼠EP3，EP4，EP1，EP2和IP受体的ki值分别为1.1、2.1、36、10和33 nM）。抑制血小板聚集，是体内血管扩张剂。

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：Prostaglandin E1 (PGE1) is a major prostaglandin found in human semen that acts as a vasodilator, a fibrinolytic agent, and an inhibitor of platelet aggregation. Additionally, PGE1 has been shown to affect protein kinase C (PKC), calcium movement, and adenylate cyclase yielding a multitude of physiological effects.A major prostaglandin that affects protein kinase C (PKC), calcium movement, and adenylate cyclaseProstaglandin E1 (PGE1) is a major prostaglandin found in human semen that acts as a vasodilator, a fibrinolytic agent, and an inhibitor of platelet aggregation. Additionally, PGE1 has been shown to affect protein kinase C (PKC), calcium movement, and adenylate cyclase yielding a multitude of physiological effects.A major prostaglandin that affects protein kinase C (PKC), calcium movement, and adenylate cyclase

ALogP：3.2

PubChem SID：488195214

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488195214

IUPAC Name：7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid

INCHI：InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1

InChi Key：GMVPRGQOIOIIMI-DWKJAMRDSA-N

Canonical SMILES：CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O

Isomeric SMILES：CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCCCCC(=O)O)O)O

WGK Germany：3

RTECS：GY4569800

PubChem CID：5280723

UN Number：2811

Packing Group：III

DrugBank Ligand：DB00770

CAS Registry No.：745-65-3

ChEBI：CHEBI15544

ChEMBL Ligand：CHEMBL495

BindingDB Ligand：50101853

Wikipedia：Prostaglandin_E1

RCSB PDB Ligand：XPG

PEP：pge1

DrugCentral Ligand：138

GPCRdb Ligand：PGE1

溶解性：溶于ethanol, 最高浓度 (mg/mL) 17.72, 最高浓度(mM) 50

密度：1.13

敏感性：对热敏感

沸点：529.28 °C/760 mmHg

熔点：114-115°C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH361 Suspected of damaging fertility or the unborn child

预防措施声明：P280,P321,P405,P501,P264,P270,P330,P203,P301+P316,P318

Class：6.1

个人防护装备：dust mask type N95 (US), Eyeshields, Faceshields, Gloves

产品包装