产品名称

英文名称：Taranabant

同义词

Taranabant、701977-09-5、MK-0364、MK 0364、MK0364、Taranabant (MK-0364)、Tranabant (MK-0364)、MK-0634、CHEMBL220360、X9U622S114、N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[(5-(trifluoromethyl)pyridin-2-yl)oxy]propanamide( MK 0364)、1

产品性质

CAS编号：701977-09-5

分子式：C27H25ClF3N3O2

分子量：515.97

PubChem编号：11226090

英文别名：Taranabant|701977-09-5|MK-0364|MK 0364|MK0364|Taranabant (MK-0364)|Tranabant (MK-0364)|MK-0634|CHEMBL220360|X9U622S114|N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[(5-(trifluoromethyl)pyridin-2-yl)oxy]propanamide( MK 0364)|1

规格或纯度：≥98%

英文名称：Taranabant

生化机理：Taranabant is a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist （CB1 Antagonist）for the Treatment of Obesity.

储存温度：-20°C储存

运输条件：超低温冰袋运输

IUPAC Name：N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl]-2-methyl-2-[5-(trifluoromethyl)pyridin-2-yl]oxypropanamide

INCHI：InChI=1S/C27H25ClF3N3O2/c1-17(34-25(35)26(2,3)36-24-12-9-21(16-33-24)27(29,30)31)23(14-18-7-10-22(28)11-8-18)20-6-4-5-19(13-20)15-32/h4-13,16-17,23H,14H2,1-3H3,(H,34,35)/t17-,23+/m0/s1

InChi Key：QLYKJCMUNUWAGO-GAJHUEQPSA-N

Canonical SMILES：CC(C(CC1=CC=C(C=C1)Cl)C2=CC=CC(=C2)C#N)NC(=O)C(C)(C)OC3=NC=C(C=C3)C(F)(F)F

Isomeric SMILES：C[C@@H]([C@@H](CC1=CC=C(C=C1)Cl)C2=CC=CC(=C2)C#N)NC(=O)C(C)(C)OC3=NC=C(C=C3)C(F)(F)F

PubChem CID：11226090

ChEMBL Ligand：CHEMBL220360

BindingDB Ligand：50200841

CAS Registry No.：701977-09-5

RCSB PDB Ligand：7DY

GPCRdb Ligand：taranabant

溶解性：Soluble in DMSO to 52 mM

象形图：

信号词：Danger

危险声明：H400 Very toxic to aquatic lifeH372 Causes damage to organs through prolonged or repeated exposure

预防措施声明：P273,P501,P264,P260,P270,P391,P319

产品包装