产品名称

英文名称：Otamixaban

同义词

1ksn、DB06635、methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate、XRP0673、XRP-0673、Otamixaban [INN]、Methyl (2R,3R)-2-(3-carbamimidoylbenzyl)-3-((4-(1-oxidopyridin-4-yl)benzoyl)amino)butanoate、NCGC003787、奥米沙班

产品性质

CAS编号：193153-04-7

分子式：C25H28N4O4

分子量：448.53

PubChem编号：5496659

别名：奥米沙班

英文别名：1ksn|DB06635|methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate|XRP0673|XRP-0673|Otamixaban [INN]|Methyl (2R,3R)-2-(3-carbamimidoylbenzyl)-3-((4-(1-oxidopyridin-4-yl)benzoyl)amino)butanoate|NCGC003787

规格或纯度：≥98%

英文名称：Otamixaban

生化机理：Otamixaban(FXV 673) is an intravenous direct factor Xa inhibitor.Otamixaban is useful for thromboembolic disorders.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Otamixaban（FXV673）是高效的fXa选择性可逆型抑制剂，Ki为0.5nM，能抑制游离型或凝血酶原酶结合型fXa。Otamixaban(FXV673) is a potent (Ki = 0.5 nM), selective, rapid acting, competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa.

ALogP：2

IUPAC Name：methyl (2R,3R)-2-[(3-carbamimidoylphenyl)methyl]-3-[[4-(1-oxidopyridin-1-ium-4-yl)benzoyl]amino]butanoate

INCHI：InChI=1S/C25H26N4O4/c1-16(22(25(31)33-2)15-17-4-3-5-21(14-17)23(26)27)28-24(30)20-8-6-18(7-9-20)19-10-12-29(32)13-11-19/h3-14,16,22H,15H2,1-2H3,(H3,26,27)(H,28,30)/t16-,22-/m1/s1

InChi Key：PFGVNLZDWRZPJW-OPAMFIHVSA-N

Canonical SMILES：CC(C(CC1=CC(=CC=C1)C(=N)N)C(=O)OC)NC(=O)C2=CC=C(C=C2)C3=CC=[N+](C=C3)[O-]

Isomeric SMILES：C[C@H]([C@@H](CC1=CC(=CC=C1)C(=N)N)C(=O)OC)NC(=O)C2=CC=C(C=C2)C3=CC=[N+](C=C3)[O-]

PubChem CID：5496659

ChEMBL Ligand：CHEMBL46618

BindingDB Ligand：50114539

RCSB PDB Ligand：FXV

CAS Registry No.：193153-04-7

Reactome Reaction：R-HSA-9681514

Reactome Drug：R-ALL-9682033

溶解性：DMSO

产品包装