产品名称

英文名称：Tos-PEG4-Boc

同义词

Tos-PEG4-t-butyl ester、217817-01-1、Tos-PEG4-t-butyl ester (Tos-PEG4-Boc)、tert-butyl 3-(2-(2-(2-(tosyloxy)ethoxy)ethoxy)ethoxy)propanoate、3-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid tert-butyl ester、tert-butyl 3-[2-(2-{2-[(4-m、对甲苯磺酸酯丙酸叔丁酯三乙二醇

产品性质

CAS编号：217817-01-1

分子式：C20H32O8S

分子量：432.53

PubChem编号：60146205

别名：对甲苯磺酸酯丙酸叔丁酯三乙二醇

英文别名：Tos-PEG4-t-butyl ester|217817-01-1|Tos-PEG4-t-butyl ester (Tos-PEG4-Boc)|tert-butyl 3-(2-(2-(2-(tosyloxy)ethoxy)ethoxy)ethoxy)propanoate|3-(2-{2-[2-(Toluene-4-sulfonyloxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid tert-butyl ester|tert-butyl 3-[2-(2-{2-[(4-m

规格或纯度：97%

英文名称：Tos-PEG4-Boc

运输条件：常规运输

产品介绍：Tos-PEG4-Boc是一种 PROTAC 连接桥 (PROTAC linker)，属于 PEG 类。Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) 可用于合成一系列 PROTAC 分子，如 BI-3663 (HY-111546)。BI-3663 是一种高度选择性的 PTK2/FAK PROTAC，具有 E3 连接酶配体，能够降解 PTK2，IC50 值为 18 nMTos-PEG4-Boc is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663 (HY-111546). BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM

IUPAC Name：tert-butyl 3-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]propanoate

INCHI：InChI=1S/C20H32O8S/c1-17-5-7-18(8-6-17)29(22,23)27-16-15-26-14-13-25-12-11-24-10-9-19(21)28-20(2,3)4/h5-8H,9-16H2,1-4H3

InChi Key：AAQWIVKRAHBPDM-UHFFFAOYSA-N

Canonical SMILES：CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCC(=O)OC(C)(C)C

Isomeric SMILES：CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCC(=O)OC(C)(C)C

PubChem CID：60146205

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

产品包装