产品名称

英文名称：NB-598

同义词

NB-598、131060-14-5、NB 598、CHEMBL27885、Benzenemethanamine, 3-([3,3'-bithiophen]-5-ylmethoxy)-N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-ethyl-、(E)-N-ethyl-6,6-dimethyl-N-[[3-[(4-thiophen-3-ylthiophen-2-yl)methoxy]phenyl]methyl]hept-2-en-4-yn-1-amine、(E)-3-

产品性质

CAS编号：131060-14-5

分子式：C27H31NOS2

分子量：449.67

PubChem编号：6443223

英文别名：NB-598|131060-14-5|NB 598|CHEMBL27885|Benzenemethanamine, 3-([3,3'-bithiophen]-5-ylmethoxy)-N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-ethyl-|(E)-N-ethyl-6,6-dimethyl-N-[[3-[(4-thiophen-3-ylthiophen-2-yl)methoxy]phenyl]methyl]hept-2-en-4-yn-1-amine|(E)-3-

英文名称：NB-598

生化机理：NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis throμgh the farnesol pathway. SE inhibitor NB-598 significantly inhibited both basal and glucose-stimulated insulin secretion from mouse pancreatic islets. CaV channels were markedly inhibited by NB-598.

储存温度：-20°C储存

运输条件：超低温冰袋运输

IUPAC Name：(E)-N-ethyl-6,6-dimethyl-N-[[3-[(4-thiophen-3-ylthiophen-2-yl)methoxy]phenyl]methyl]hept-2-en-4-yn-1-amine

INCHI：InChI=1S/C27H31NOS2/c1-5-28(14-8-6-7-13-27(2,3)4)18-22-10-9-11-25(16-22)29-19-26-17-24(21-31-26)23-12-15-30-20-23/h6,8-12,15-17,20-21H,5,14,18-19H2,1-4H3/b8-6+

InChi Key：KIRGLCXNEVICOG-SOFGYWHQSA-N

Canonical SMILES：CCN(CC=CC#CC(C)(C)C)CC1=CC(=CC=C1)OCC2=CC(=CS2)C3=CSC=C3

Isomeric SMILES：CCN(C/C=C/C#CC(C)(C)C)CC1=CC(=CC=C1)OCC2=CC(=CS2)C3=CSC=C3

PubChem CID：6443223

ChEMBL Ligand：CHEMBL27885

CAS Registry No.：131060-14-5

RCSB PDB Ligand：EMV

溶解性：DMSO

产品包装