产品名称

英文名称：Methyldopa Sesquihydrate

同义词

41372-08-1、METHYLDOPA SESQUIHYDRATE、alpha-Methyl-L-dopa sesquihydrate、alpha-Methyldopa sesquihydrate、MK-351 hydrate;Methyldopa hydrate、(2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;hydrate、(-)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine sesqu、左旋甲基多巴

产品性质

CAS编号：41372-08-1

分子式：C10H13NO4·1.5H2O

分子量：238.24

PubChem编号：18530292

别名：左旋甲基多巴

英文别名：41372-08-1|METHYLDOPA SESQUIHYDRATE|alpha-Methyl-L-dopa sesquihydrate|alpha-Methyldopa sesquihydrate|MK-351 hydrate;Methyldopa hydrate|(2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;hydrate|(-)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine sesqu

规格或纯度：≥98%

英文名称：Methyldopa Sesquihydrate

生化机理：L-α-Methyl-DOPA · sesquihydrate is a DDC (L-Aromatic amino acid decarboxylase) inhibitor. Adrenergic inhibiting agent used for antihypertensive treatment.α2 adrenoceptor agonist. Competitive DOPA decarboxylase inhibitor. Centrally and peripherally acting. Depletes tissue levels of norepinephrine. Shows antihypertensive effects in vivo. Orally active.

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

备注：卖完停产，不再备货.如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Methyldopa 是DOPA 脱羧酶竞争性抑制剂，ED50为21.8 mg/kg。L-α-Methyl-DOPA · sesquihydrate is a DDC (L-Aromatic amino acid decarboxylase) inhibitor. Adrenergic inhibiting agent used for antihypertensive treatment.Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.L-α-Methyl-DOPA · sesquihydrate is a DDC (L-Aromatic amino acid decarboxylase) inhibitor. Adrenergic inhibiting agent used for antihypertensive treatment.

ALogP：-1.9

IUPAC Name：(2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;hydrate

INCHI：InChI=1S/C10H13NO4.H2O/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6;/h2-4,12-13H,5,11H2,1H3,(H,14,15);1H2/t10-;/m0./s1

InChi Key：XDJUBZFLFDODNF-PPHPATTJSA-N

Canonical SMILES：CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N.O

Isomeric SMILES：C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)N.O

关联CAS：555-30-6

PubChem CID：18530292

溶解性：Soluble in water (sparingly), 0.1M HCl (5 %, clear, colorless to faint yellow solution), and dilute mineral acids. Almost insoluble in common organic solvents.

敏感性：对光和空气敏感

熔点：>300°C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH412 Harmful to aquatic life with long lasting effectsH302 Harmful if swallowedH372 Causes damage to organs through prolonged or repeated exposureH361 Suspected of damaging fertility or the unborn child

预防措施声明：P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P362+P364,P330,P203,P264+P265,P301+P317,P318,P337+P317,P332+P317,P319

产品包装