产品名称

英文名称：Valbenazine

同义词

Valbenazine、1025504-45-3、Ingrezza、NBI-98854、Mt-5199、NBI 98854、UNII-54K37P50KH、54K37P50KH、ValbenazineNBI-98854、(2R,3R,11bR)-9,10-Dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H- benzo(a)quinolizin-2-yl L-valinate、L-Valine, (2R,3R,11bR)-1,3,4,6,7,11

产品性质

CAS编号：1025504-45-3

分子式：C24H38N2O4

分子量：418.57

PubChem编号：24795069

英文别名：Valbenazine|1025504-45-3|Ingrezza|NBI-98854|Mt-5199|NBI 98854|UNII-54K37P50KH|54K37P50KH|ValbenazineNBI-98854|(2R,3R,11bR)-9,10-Dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H- benzo(a)quinolizin-2-yl L-valinate|L-Valine, (2R,3R,11bR)-1,3,4,6,7,11

规格或纯度：97%

英文名称：Valbenazine

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Valbenazine (NBI-98854) 是一种囊泡单胺类转运 2 (VMAT2) 抑制剂，Ki 为 110-190 nM

ALogP：4.3

IUPAC Name：[(2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] (2S)-2-amino-3-methylbutanoate

INCHI：InChI=1S/C24H38N2O4/c1-14(2)9-17-13-26-8-7-16-10-21(28-5)22(29-6)11-18(16)19(26)12-20(17)30-24(27)23(25)15(3)4/h10-11,14-15,17,19-20,23H,7-9,12-13,25H2,1-6H3/t17-,19-,20-,23+/m1/s1

InChi Key：GEJDGVNQKABXKG-CFKGEZKQSA-N

Canonical SMILES：CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1OC(=O)C(C(C)C)N)OC)OC

Isomeric SMILES：CC(C)C[C@@H]1CN2CCC3=CC(=C(C=C3[C@H]2C[C@H]1OC(=O)[C@H](C(C)C)N)OC)OC

PubChem CID：24795069

ChEMBL Ligand：CHEMBL2364639

CAS Registry No.：1025504-45-3

DrugCentral Ligand：5227

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH373 Causes damage to organs through prolonged or repeated exposureH336 May cause drowsiness or dizziness

预防措施声明：P261,P321,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P330,P301+P316,P319

产品包装