产品名称

英文名称：Idebenone

同义词

idebenone、58186-27-9、2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione、Idebenona、Idebenonum、Sovrima、hydroxydecyl ubiquinone、CV 2619、CV-2619、Oristar hdu、BRN 2001459、CHEBI31687、2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquino、艾地苯醌,2-(10-羟基癸基)-5,6-二甲氧基-3-甲基-1,4-苯醌

产品性质

CAS编号：58186-27-9

分子式：C19H30O5

分子量：338.44

MDL号：MFCD00274552

PubChem编号：3686

别名：艾地苯醌,2-(10-羟基癸基)-5,6-二甲氧基-3-甲基-1,4-苯醌

英文别名：idebenone|58186-27-9|2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione|Idebenona|Idebenonum|Sovrima|hydroxydecyl ubiquinone|CV 2619|CV-2619|Oristar hdu|BRN 2001459|CHEBI31687|2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquino

规格或纯度：≥98%

英文名称：Idebenone

生化机理：Idebenone, a neuroprotective agent, has been shown to act as a free radical scavenger and protect mitochondrial membranes against lipid peroxidation. This compound has also been found to prevent platelet aggregation and recover cholinergic and monoaminergic changes in murine models. Other studies show that Idebenone displays a capacity to increase nerve growth factor production in cultured rat astrocytes. Additionally, this agent has been reported to dose-dependently inhibit enzymatic metabolism of Arachidonic Acid in astroglial homogenates.Potent antioxidant and neuroprotective agent. Coenzyme Q analogue. Active in vivo.

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Idebenone是一种辅酶Q10（CoQ10）的合成类似物，是一种大脑兴奋剂。An antioxidant and neuroprotective agent.Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant.An antioxidant and neuroprotective agent.applicationIdebenone has been usedto treat mutant myocilin (mMYOC) cells for drug treatment assay，to validate C2C12 secondary cell screening assayto treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs

ALogP：4.3

PubChem SID：488179783

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488179783

IUPAC Name：2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione

INCHI：InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3

InChi Key：JGPMMRGNQUBGND-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO

Isomeric SMILES：CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO

RTECS：GU5290000

PubChem CID：3686

Reaxy-Rn：2001459

溶解性：Soluble in DMSO (>25 mg/ml), ethanol (>25 mg/ml), methanol, and chloroform. Insoluble in water.

熔点：53℃

Merck Index：4888

产品包装