产品名称

英文名称：Clindamycin Phosphate

同义词

Clindamycin phosphate、24729-96-2、Cleocin phosphate、Clindamycin 2-phosphate、Clindets、Cleocin T、Clindagel、Clindesse、Evoclin、Clinda-Derm、Dalacin P、CLINDAMYCIN-2-PHOSPHATE、Clindamax、Clindamycin 2-dihydrogen phosphate、Dalacin T、Clindamycin injection、7(S)-Chlor、磷酸克林霉素酯、克林霉素磷酸酯、克林霉素 磷酸盐、克林霉素 2-磷酸酯

产品性质

CAS编号：24729-96-2

分子式：C18H34ClN2O8PS

分子量：504.96

EC号：246-433-0

MDL号：MFCD07793328

PubChem编号：443385

别名：磷酸克林霉素酯|克林霉素磷酸酯|克林霉素 磷酸盐|克林霉素 2-磷酸酯

英文别名：Clindamycin phosphate|24729-96-2|Cleocin phosphate|Clindamycin 2-phosphate|Clindets|Cleocin T|Clindagel|Clindesse|Evoclin|Clinda-Derm|Dalacin P|CLINDAMYCIN-2-PHOSPHATE|Clindamax|Clindamycin 2-dihydrogen phosphate|Dalacin T|Clindamycin injection|7(S)-Chlor

规格或纯度：≥96%

英文名称：Clindamycin Phosphate

生化机理：Clindamycin Phosphate (U-28508E) is an antibiotic with anti-inflammatory properties. The compound is a potent antibiotic against anaerobic and gram-positive bacteria. Studies show that Clindamycin associates with the 50S ribosomal subunit, which leads to the inhibition of protein synthesis. Clindamycin has been used in multiple acne vulgaris studies. Clindamycin Phosphate (U-28508E) is an inhibitor of TDP1. Spectrum of Activity Gram positive cocci and taxoplasma. Especially active against anaerobic bacteria. Mode of Action Inhibits protein synthesis in bacterial by binding the 50s ribosomal subunit.

应用：An antibiotic with anti-inflammatory properties.

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

产品介绍：Clindamycin Phosphate是一种林可酰胺类抗生素，作用于 Plasmodium falciparum，IC50为12 nMClindamycin is a lincosamide antibiotic which is considered as a semisynthetic derivative of lincomycin. It is mainly used as an antimicrobial agent.An antibiotic with anti-inflammatory properties.Clindamycin Phosphate is a lincosamide antibiotic for Plasmodium falciparum with IC50 of 12 nM.Clindamycin is a lincosamide antibiotic which is considered as a semisynthetic derivative of lincomycin. It is mainly used as an antimicrobial agent.An antibiotic with anti-inflammatory properties.

ALogP：-1.2

IUPAC Name：[(2R,3R,4S,5R,6R)-6-[(1S,2S)-2-chloro-1-[[(2S,4R)-1-methyl-4-propylpyrrolidine-2-carbonyl]amino]propyl]-4,5-dihydroxy-2-methylsulfanyloxan-3-yl] dihydrogen phosphate

INCHI：InChI=1S/C18H34ClN2O8PS/c1-5-6-10-7-11(21(3)8-10)17(24)20-12(9(2)19)15-13(22)14(23)16(18(28-15)31-4)29-30(25,26)27/h9-16,18,22-23H,5-8H2,1-4H3,(H,20,24)(H2,25,26,27)/t9-,10+,11-,12+,13+,14-,15+,16+,18+/m0/s1

InChi Key：UFUVLHLTWXBHGZ-MGZQPHGTSA-N

Canonical SMILES：CCCC1CC(N(C1)C)C(=O)NC(C2C(C(C(C(O2)SC)OP(=O)(O)O)O)O)C(C)Cl

Isomeric SMILES：CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)OP(=O)(O)O)O)O)[C@H](C)Cl

WGK Germany：3

RTECS：GF2625000

PubChem CID：443385

溶解性：Soluble in water, and DMSO

比旋光度：122° (C=1,H2O)

熔点：114°C

象形图：

信号词：Warning

危险声明：H319 Causes serious eye irritationH302 Harmful if swallowedH317 May cause an allergic skin reactionH316 Causes mild skin irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P501,P264,P270,P272,P333+P313,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317

Merck Index：2356

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