产品名称

英文名称：MK-0974

同义词

Telcagepant、781649-09-0、MK-0974、MK0974、MK 0974、MK 0974, Telcagepant、Telcagepant (USAN)、Telcagepant [USAN]、CHEMBL236593、D42O649ALL、N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-

产品性质

CAS编号：781649-09-0

分子式：C26H27F5N6O3

分子量：566.54

PubChem编号：11319053

英文别名：Telcagepant|781649-09-0|MK-0974|MK0974|MK 0974|MK 0974, Telcagepant|Telcagepant (USAN)|Telcagepant [USAN]|CHEMBL236593|D42O649ALL|N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-

规格或纯度：≥99%

英文名称：MK-0974

生化机理：MK-0974 is a highly potent, selective, and orally bioavailable CGRP receptor antagonist, which may be valuable in the acute treatment of migraine.

储存温度：-20°C储存

运输条件：超低温冰袋运输

ALogP：3

IUPAC Name：N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide

INCHI：InChI=1S/C26H27F5N6O3/c27-18-4-1-3-17(21(18)28)15-6-7-19(23(38)36(13-15)14-26(29,30)31)33-24(39)35-11-8-16(9-12-35)37-20-5-2-10-32-22(20)34-25(37)40/h1-5,10,15-16,19H,6-9,11-14H2,(H,33,39)(H,32,34,40)/t15-,19-/m1/s1

InChi Key：CGDZXLJGHVKVIE-DNVCBOLYSA-N

Canonical SMILES：C1CC(C(=O)N(CC1C2=C(C(=CC=C2)F)F)CC(F)(F)F)NC(=O)N3CCC(CC3)N4C5=C(NC4=O)N=CC=C5

Isomeric SMILES：C1C[C@H](C(=O)N(C[C@@H]1C2=C(C(=CC=C2)F)F)CC(F)(F)F)NC(=O)N3CCC(CC3)N4C5=C(NC4=O)N=CC=C5

PubChem CID：11319053

Wikipedia：Telcagepant

ChEMBL Ligand：CHEMBL236593

BindingDB Ligand：50224431

CAS Registry No.：781649-09-0

RCSB PDB Ligand：N7R

溶解性：DMSO

产品包装