产品名称

英文名称：Vaniprevir

同义词

Vaniprevir、923590-37-8、MK-7009、vanihep、MK7009、Vaniprevir [USANINN]、UNII-CV3X74AO1H、CV3X74AO1H、Cyclopropanecarboxamide, N-(((6-(2-carboxy-2,3-dihydro-1H-isoindol-4-yl)-2,2-dimethylhexyl)oxy)carbonyl)-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-N-(cyc

产品性质

CAS编号：923590-37-8

分子式：C38H55N5O9S

分子量：757.95

PubChem编号：24765256

英文别名：Vaniprevir|923590-37-8|MK-7009|vanihep|MK7009|Vaniprevir [USANINN]|UNII-CV3X74AO1H|CV3X74AO1H|Cyclopropanecarboxamide, N-(((6-(2-carboxy-2,3-dihydro-1H-isoindol-4-yl)-2,2-dimethylhexyl)oxy)carbonyl)-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-N-(cyc

英文名称：Vaniprevir

生化机理：vaniprevir (MK-7009) is a macrocyclic hepatitis C virus NS3/4a protease inhibitor, is active against both the genotype 1 and genotype 2 NS3/4a protease enzymes. vaniprevir (MK-7009) has good plasma exposure and excellent liver exposure in multiple species.

储存温度：-20°C储存

运输条件：超低温冰袋运输

ALogP：5.1

IUPAC Name：(1R,21S,24S)-21-tert-butyl-N-[(1R,2R)-1-(cyclopropylsulfonylcarbamoyl)-2-ethylcyclopropyl]-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.14,7.06,11]heptacosa-6(11),7,9-triene-24-carboxamide

INCHI：InChI=1S/C38H55N5O9S/c1-7-25-18-38(25,33(46)41-53(49,50)27-14-15-27)40-31(44)29-17-26-20-43(29)32(45)30(36(2,3)4)39-34(47)51-22-37(5,6)16-9-8-11-23-12-10-13-24-19-42(21-28(23)24)35(48)52-26/h10,12-13,25-27,29-30H,7-9,11,14-22H2,1-6H3,(H,39,47)(H,40,44)(H,41,46)/t25-,26-,29+,30-,38-/m1/s1

InChi Key：KUQWGLQLLVFLSM-ONAXAZCASA-N

Canonical SMILES：CCC1CC1(C(=O)NS(=O)(=O)C2CC2)NC(=O)C3CC4CN3C(=O)C(NC(=O)OCC(CCCCC5=C6CN(CC6=CC=C5)C(=O)O4)(C)C)C(C)(C)C

Isomeric SMILES：CC[C@@H]1C[C@@]1(C(=O)NS(=O)(=O)C2CC2)NC(=O)[C@@H]3C[C@@H]4CN3C(=O)[C@@H](NC(=O)OCC(CCCCC5=C6CN(CC6=CC=C5)C(=O)O4)(C)C)C(C)(C)C

PubChem CID：24765256

CAS Registry No.：923590-37-8

ChEMBL Ligand：CHEMBL4525964

DrugBank Ligand：DB11929

BindingDB Ligand：103836

RCSB PDB Ligand：SU3

溶解性：DMSO

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposure

预防措施声明：P501,P260,P319

产品包装