产品名称

英文名称：Capadenoson

同义词

Capadenoson、544417-40-5、BAY 68-4986、Capadenoson [INN]、BAY-68-4986、O519NVW73R、2-amino-6-[[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methylsulfanyl]-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile、CHEMBL3235279、2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol

产品性质

CAS编号：544417-40-5

分子式：C25H18ClN5O2S2

分子量：520.03

PubChem编号：9936489

英文别名：Capadenoson|544417-40-5|BAY 68-4986|Capadenoson [INN]|BAY-68-4986|O519NVW73R|2-amino-6-[[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methylsulfanyl]-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile|CHEMBL3235279|2-amino-6-({[2-(4-chlorophenyl)-1,3-thiazol

规格或纯度：≥98%

英文名称：Capadenoson

生化机理：Capadenoson (BAY 68-4986) is a new adenosine A1 receptor agonist. Studies showed that long-term therapy with Capadenoson improves phosphorylation and total protein level of PGC-1α in LV myocardium of HF dogs. Clinical trial found that in patients with stable angina Capadenoson lowers exercise HR at comparable maximum workload, which is associated with improved total exercise time and prolongation of time to ischaemia.

储存温度：-20°C储存

运输条件：超低温冰袋运输

ALogP：5.1

IUPAC Name：2-amino-6-[[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methylsulfanyl]-4-[4-(2-hydroxyethoxy)phenyl]pyridine-3,5-dicarbonitrile

INCHI：InChI=1S/C25H18ClN5O2S2/c26-17-5-1-16(2-6-17)24-30-18(13-34-24)14-35-25-21(12-28)22(20(11-27)23(29)31-25)15-3-7-19(8-4-15)33-10-9-32/h1-8,13,32H,9-10,14H2,(H2,29,31)

InChi Key：CITWCLNVRIKQAF-UHFFFAOYSA-N

Canonical SMILES：C1=CC(=CC=C1C2=C(C(=NC(=C2C#N)SCC3=CSC(=N3)C4=CC=C(C=C4)Cl)N)C#N)OCCO

Isomeric SMILES：C1=CC(=CC=C1C2=C(C(=NC(=C2C#N)SCC3=CSC(=N3)C4=CC=C(C=C4)Cl)N)C#N)OCCO

PubChem CID：9936489

CAS Registry No.：544417-40-5

ChEMBL Ligand：CHEMBL3235279

GPCRdb Ligand：capadenoson

溶解性：DMSO

象形图：

信号词：Danger

危险声明：H370 Causes damage to organsH361 Suspected of damaging fertility or the unborn child

预防措施声明：P280,P321,P405,P501,P264,P260,P270,P203,P318,P308+P316

产品包装