产品名称

英文名称：CORT-108297

同义词

CORT-108297、1018679-79-2、Cort108297、CORT 108297、ADS-108297、CHEMBL271220、(R)-4A-(ethoxymethyl)-1-(4-fluorophenyl)-6-((4-(trifluoromethyl)phenyl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinoline、A17W0640NB、(R)-4a-(Ethoxymethyl)-1-(4-fluorophen

产品性质

CAS编号：1018679-79-2

分子式：C26H25F4N3O3S

分子量：535.55

PubChem编号：44454750

英文别名：CORT-108297|1018679-79-2|Cort108297|CORT 108297|ADS-108297|CHEMBL271220|(R)-4A-(ethoxymethyl)-1-(4-fluorophenyl)-6-((4-(trifluoromethyl)phenyl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinoline|A17W0640NB|(R)-4a-(Ethoxymethyl)-1-(4-fluorophen

规格或纯度：97%

英文名称：CORT-108297

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Cort108297 是一种高亲和性的特异性糖皮质激素受体 (GR) 拮抗剂，Ki 值为 0.45 nM。 Cort108297 is a specific glucocorticoid receptor (GR) antagonist. Cort108297 has a high affinity for GRs with a Ki of 0.45 nM.

ALogP：4.4

IUPAC Name：(4aR)-4a-(ethoxymethyl)-1-(4-fluorophenyl)-6-[4-(trifluoromethyl)phenyl]sulfonyl-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinoline

INCHI：InChI=1S/C26H25F4N3O3S/c1-2-36-17-25-14-18-15-31-33(22-7-5-21(27)6-8-22)24(18)13-20(25)11-12-32(16-25)37(34,35)23-9-3-19(4-10-23)26(28,29)30/h3-10,13,15H,2,11-12,14,16-17H2,1H3/t25-/m1/s1

InChi Key：SLKURXRZHJOZOD-RUZDIDTESA-N

Canonical SMILES：CCOC[C@]12CC3=C(C=C1CCN(C2)S(=O)(=O)C4=CC=C(C=C4)C(F)(F)F)N(N=C3)C5=CC=C(C=C5)F

Isomeric SMILES：CCOC[C@]12CC3=C(C=C1CCN(C2)S(=O)(=O)C4=CC=C(C=C4)C(F)(F)F)N(N=C3)C5=CC=C(C=C5)F

PubChem CID：44454750

溶解性：DMSO 30 mg/mL (56.02 mM)

信号词：Warning

危险声明：H315 Causes skin irritationH335 May cause respiratory irritationH302 Harmful if swallowedH320 Causes eye irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P301+P312

产品包装