产品名称

英文名称：Trospium chloride

同义词

Trospikan、TROSPIUM CHLORIDE [ORANGE BOOK]、Trospium chloride [USANUSPINNBANJAN]、Flotros、HY-B0461、TROSPIUM CHLORIDE [USAN]、Trospiumchlorid、1E6682427E、Chlorure de trospium、Spiro (8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium), 3-((hydroxydiphenylacetyl、曲司氯胺

产品性质

CAS编号：10405-02-4

分子式：C25H30NO3.Cl

分子量：427.96

MDL号：MFCD00865254

PubChem编号：5284631

别名：曲司氯胺

英文别名：Trospikan|TROSPIUM CHLORIDE [ORANGE BOOK]|Trospium chloride [USANUSPINNBANJAN]|Flotros|HY-B0461|TROSPIUM CHLORIDE [USAN]|Trospiumchlorid|1E6682427E|Chlorure de trospium|Spiro (8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium), 3-((hydroxydiphenylacetyl

规格或纯度：≥99%

英文名称：Trospium chloride

生化机理：Trospium chloride is a tropine derivative with anti-cholinergic activity. Trospium chloride is a competitive muscarinic cholinergic receptor antagonist. This compound is effective at controlling muscle spasm in extracted rat bladder tissue by blocking the opening of ion channels by acetylcholine.Competitive M2 and M3 mAChR antagonist. Shows antispasmodic and renoprotective effects in vivo. Weakly blood-brain barrier permeable. Orally active.

应用：An antimuscarinic compound that inhibits mAChR M

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Trospium chloride 是一种竞争性的毒蕈碱型乙酰胆碱受体拮抗剂。An antimuscarinic compound that inhibits mAChR MTrospium chloride is a competitive muscarinic cholinergic receptor antagonist.An antimuscarinic compound that inhibits mAChR M;Trospium氯化物是毒蕈碱胆碱受体拮抗剂。

PubChem SID：488195296

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488195296

IUPAC Name：[(1R,5S)-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl] 2-hydroxy-2,2-diphenylacetate;chloride

INCHI：InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23?;

InChi Key：RVCSYOQWLPPAOA-DHWZJIOFSA-M

Canonical SMILES：C1CC[N+]2(C1)C3CCC2CC(C3)OC(=O)C(C4=CC=CC=C4)(C5=CC=CC=C5)O.[Cl-]

Isomeric SMILES：C1CC[N+]2(C1)[C@@H]3CC[C@H]2CC(C3)OC(=O)C(C4=CC=CC=C4)(C5=CC=CC=C5)O.[Cl-]

PubChem CID：5284631

溶解性：Soluble in DMSO and Methanol

熔点：262 °C(dec.)

象形图：

信号词：Warning

危险声明：H412 Harmful to aquatic life with long lasting effectsH302 Harmful if swallowedH312 Harmful in contact with skinH332 Harmful if inhaled

预防措施声明：P261,P273,P280,P302+P352,P321,P501,P264,P271,P270,P304+P340,P362+P364,P330,P301+P317,P317

Merck Index：9786

产品包装