产品名称

英文名称：Aloe-emodin

同义词

Aloe-emodin、Aloe emodin、481-72-1、Aloeemodin、Rhabarberone、Aloe-emodine、3-Hydroxymethylchrysazine、1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione、3-Hydroxymethylchrysazin、EMODINE、1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone、1,8-Dihydroxy-3-hydroxymethy、芦荟泻素、1,8-二羟基-3-(羟甲基)蒽甲苯, 3-羟甲基白杨嗪, 弹力素, 1,8-二羟基3-羟甲基蒽甲苯

产品性质

CAS编号：481-72-1

分子式：C15H10O5

分子量：270.24

Beilstein号：2059062

EC号：207-571-7

MDL号：MFCD00017373

PubChem编号：10207

别名：芦荟泻素|1,8-二羟基-3-(羟甲基)蒽甲苯, 3-羟甲基白杨嗪, 弹力素, 1,8-二羟基3-羟甲基蒽甲苯

英文别名：Aloe-emodin|Aloe emodin|481-72-1|Aloeemodin|Rhabarberone|Aloe-emodine|3-Hydroxymethylchrysazine|1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione|3-Hydroxymethylchrysazin|EMODINE|1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone|1,8-Dihydroxy-3-hydroxymethy

规格或纯度：分析标准品

英文名称：Aloe-emodin

生化机理：Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin.

应用：泻药/泻剂化合物;内源性乙酰胆碱的释放增加了肠道平滑肌收缩。遗传毒性和致突变性似乎是由芦荟大黄素由于抑制拓扑异构酶II活性

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：易溶于热乙醇，在苯及乙醚中呈黄色，在氨水和硫酸中呈绯红色，属蒽醌类化合物，在酸性溶液中被还原则生成蒽酚及其互变异构体的蒽酮。 泻药/泻剂化合物;内源性乙酰胆碱的释放增加了肠道平滑肌收缩。遗传毒性和致突变性似乎是由芦荟大黄素由于抑制拓扑异构酶II活性

IUPAC Name：1,8-dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione

INCHI：InChI=1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2

InChi Key：YDQWDHRMZQUTBA-UHFFFAOYSA-N

Canonical SMILES：C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO

Isomeric SMILES：C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO

WGK Germany：3

RTECS：CB6712200

PubChem CID：10207

密度：1.592

敏感性：对热敏感

熔点：223-224°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

Merck Index：306

个人防护装备：dust mask type N95 (US),Eyeshields,Gloves

产品包装