产品名称

英文名称：Eltrombopag

同义词

BCP9000641、D02363、CHEBI85010、EN300-1709152、XDXWLKQMMKQXPV-UHFFFAOYSA-N、SB497115、SB-497115、3'-[(2Z)- [1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid、3'-{2-[1-(3,4-dimethylphen、伊屈泼帕

产品性质

CAS编号：496775-61-2

分子式：C25H22N4O4

分子量：442.47

PubChem编号：135449332

别名：伊屈泼帕

英文别名：BCP9000641|D02363|CHEBI85010|EN300-1709152|XDXWLKQMMKQXPV-UHFFFAOYSA-N|SB497115|SB-497115|3'-[(2Z)- [1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid|3'-{2-[1-(3,4-dimethylphen

规格或纯度：≥99%

英文名称：Eltrombopag

生化机理：An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：5mg、10mg、25mg、50mg、100mg卖完停产，不再备货

产品介绍：Eltrombopag 是小分子，c-mpl (TpoR) 受体激动剂，抑制 hERG K+通道尾电流，IC50为0.69 μM。An agonist of the thrombopoietin receptorEltrombopag is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR).An agonist of the thrombopoietin receptor

IUPAC Name：3-[3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid

INCHI：InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,28,30H,1-3H3,(H,32,33)

InChi Key：SVOQIEJWJCQGDQ-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(=O)O)C

Isomeric SMILES：CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC=CC(=C3O)C4=CC(=CC=C4)C(=O)O)C

PubChem CID：135449332

ChEMBL Ligand：CHEMBL461101

DrugBank Ligand：DB06210

Wikipedia：Eltrombopag

CAS Registry No.：496775-61-2

DrugCentral Ligand：4399

溶解性：25°C DMSO 89 mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL

象形图：

信号词：Danger

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH302 Harmful if swallowedH318 Causes serious eye damageH410 Very toxic to aquatic life with long lasting effects

预防措施声明：P273,P280,P501,P264,P260,P270,P391,P330,P264+P265,P301+P317,P305+P354+P338,P317,P319

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