产品名称

英文名称：Pancuronium dibromide

同义词

PANCURONIUM BROMIDE、Pancuronium dibromide、15500-66-0、Pavulon、Mioblock、ORG NA 97、Pancuronii bromidum、bromurex、Bromuro de pancuronio、Bromure de pancuronium、Pancuronium (dibromide)、ORG-NA 97、CHEBI7908、HSDB 3244、EINECS 239-532-5、UNII-U9LY9Y75X2、ORG-NA-97、NSC、泮库溴铵、二溴化潘可罗宁、1,1'-[(2β,3α,5α,16β,17β)-3,17-双(乙酰氧基)雄烷-2,16-二基]双(1-甲基哌啶鎓)二溴化物

产品性质

CAS编号：15500-66-0

分子式：C35H60Br2N2O4

分子量：732.67

Beilstein号：4226892

EC号：239-532-5

MDL号：MFCD00079223

PubChem编号：27350

别名：泮库溴铵|二溴化潘可罗宁|1,1'-[(2β,3α,5α,16β,17β)-3,17-双(乙酰氧基)雄烷-2,16-二基]双(1-甲基哌啶鎓)二溴化物

英文别名：PANCURONIUM BROMIDE|Pancuronium dibromide|15500-66-0|Pavulon|Mioblock|ORG NA 97|Pancuronii bromidum|bromurex|Bromuro de pancuronio|Bromure de pancuronium|Pancuronium (dibromide)|ORG-NA 97|CHEBI7908|HSDB 3244|EINECS 239-532-5|UNII-U9LY9Y75X2|ORG-NA-97|NSC

规格或纯度：≥99%

英文名称：Pancuronium dibromide

生化机理：Pancuronium dibromide is a competitive AChR antagonist (IC50 = 5.5 nM) and acts as a skeletal muscle relaxant. Pancuronium dibromide interrupts neuromuscular transmission by competing with acetylcholine for receptor sites on the motor end-plate. Pancuronium dibromide is a non-depolarizing agent.Competitive nicotinic acetylcholine receptor (nAChR) antagonist. Displaces acetylcholine from nAChRs (IC 50 = 5.5 nM). Neuromuscular blocker and muscle relaxant.

储存温度：2-8°C储存,避光,充氩

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Pancuronium dibromide是一种竞争性的乙酰胆碱受体拮抗剂，IC50为5.5±0.5 nM。A nicotine neuromuscular antagonist.Pancuronium dibromide is a competitive acetylcholine antagonist with an IC50 of 5.5 nM.A nicotine neuromuscular antagonist.

IUPAC Name：[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-10,13-dimethyl-2,16-bis(1-methylpiperidin-1-ium-1-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate;dibromide

INCHI：InChI=1S/C35H60N2O4.2BrH/c1-24(38)40-32-21-26-13-14-27-28(35(26,4)23-31(32)37(6)19-11-8-12-20-37)15-16-34(3)29(27)22-30(33(34)41-25(2)39)36(5)17-9-7-10-18-36;;/h26-33H,7-23H2,1-6H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1

InChi Key：NPIJXCQZLFKBMV-YTGGZNJNSA-L

Canonical SMILES：CC(=O)OC1CC2CCC3C(C2(CC1[N+]4(CCCCC4)C)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-].[Br-]

Isomeric SMILES：CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@@H]([C@]2(C[C@@H]1[N+]4(CCCCC4)C)C)CC[C@]5([C@H]3C[C@@H]([C@@H]5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-].[Br-]

WGK Germany：3

RTECS：TN4930000

PubChem CID：27350

DrugBank Ligand：DB01337

Wikipedia：Pancuronium_bromide

CAS Registry No.：15500-66-0

ChEMBL Ligand：CHEMBL185073

DrugCentral Ligand：2052

溶解性：Soluble in water (100 mM), ethanol (100 mg/ml at 25 °C), and DMSO (100 mg/ml at 25 °C).

敏感性：对湿度、光线、空气敏感

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH311 Toxic in contact with skinH331 Toxic if inhaled

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P330,P361+P364,P301+P316,P316

个人防护装备：dust mask type N95 (US), Eyeshields, Faceshields, Gloves

产品包装